PEEP does not strictly induce alveolar recruitment but PEEP avoids alveolar derecruitment by maintaining open alveoli. Thus, protective ventilation strategies may improve clinical outcomes
Because prone positioning lessens heterogeneity of regional lung strain and decreases chest wall compliance [42], higher PEEP may be less likely to contribute to regional hyperinflation with proning [40]. When considering ventilator settings for the prone ARDS patient, at a minimum patients should ...
Ventilator-associated pneumonia (VAP) remains a feared complication in intensive care unit (ICU) and high-risk surgical postoperative patients [1]. VAP is associated with substantial excess morbidity [2–4] and may suppress survival [5–9]. On average 10-20% of ICU patients ventilated for >2...
The overall approach relies on the ability to identify patient-specific parameters from data that are both patient-specific and time-varying, and thus manage the intra- and inter-patient variability that defines the typical ICU patient. As a result, such “sensitivities” can be the key to virt...
predispose the lung to secondary ventilator-induced lung injury (VILI). It is our viewpoint that the acutely injured lung can be recruited and stabilized with a mechanical breath until it heals, much like casting a broken bone until it mends. If the lung can be “casted” with a mechanical...