We performed a Pubmed search of articles addressing the management of ventilator-associated pneumonia (VAP). Immunocompromised patients, children and VAP due to multi-drug resistant pathogens were excluded from the analysis. When facing a patient with VAP, it's important to address a few key ...
How- ever, a subset of failed-to-wean patients whose SvO2 does not decrease has been described [45]. These patients do not have increased oxygen consumption during weaning failure, possibly due to respiratory center depression in some of the cases. Today, pulmonary artery catheters are ...
Airless tissue is not likely to be subject to ventilator-induced lung injury – the adjacent healthy lung is. In many instances the pressure cost of recruitment may exceed the benefit of recruiting a few more units. Apart from initial PEEP selection, where RMs are essential, RMs are logically...
Ventilator-associated pneumonia (VAP) remains a feared complication in intensive care unit (ICU) and high-risk surgical postoperative patients [1]. VAP is associated with substantial excess morbidity [2–4] and may suppress survival [5–9]. On average 10-20% of ICU patients ventilated for >2...
“a controlled mechanical ventilation volume (pressure)” transfers to the uncontrolled or independent output pressure (volume) response [78,79,80,142,143,144,145,146,147,148,149,150,151], where this elastance is directly related to the work of breathing and ventilator driving pressure clinicians...
On a pressure-time waveform, the curve during the expiratory phase does not return to the baseline rapidly as it normally would. It eventually reaches the baseline. This may be a result of:A. An obstruction in the expiratory line B. PEEP set above zero baselineC. NEEPD. A leak in the...
“a controlled mechanical ventilation volume (pressure)” transfers to the uncontrolled or independent output pressure (volume) response [78,79,80,142,143,144,145,146,147,148,149,150,151], where this elastance is directly related to the work of breathing and ventilator driving pressure clinicians...
predispose the lung to secondary ventilator-induced lung injury (VILI). It is our viewpoint that the acutely injured lung can be recruited and stabilized with a mechanical breath until it heals, much like casting a broken bone until it mends. If the lung can be “casted” with a mechanical...
Hasan MS, Szczeklik W, Rios F, Amato MBP, Berwanger O, Ribeiro de Carvalho CR (2017) Effect of lung recruitment and titrated positive end-expiratory pressure (PEEP) vs low PEEP on mortality in patients with acute respiratory distress syndrome: a randomized clinical trial. JAMA 318:1335–1345...
Four groups of animals were studied and in all four groups the lungs were ventilated with a very high static strain (2.5) at total lung capacity (TLC). High dynamic strain was caused by the tidal volume (VT) being 100% of the lung volume with no positive end-expiratory pressure (VPEEP...