Paramyxoviruses including measles, Nipah, and parainfluenza viruses are public health threats with pandemic potential. Human parainfluenza virus type 3 (HPIV3) is a leading cause of illness in pediatric, older, and immunocompromised populations. There ar
Continued surveillance of RSV infections will be necessary to detect early epidemic in order to adapt the prophylaxis of young infants at risk (especially very premature infants) with palivizumab and to prepare the healthcare system. 2.1.3. Rotavirus The incidence of acute diarrhea illnesses followed...
(palivizumab) shows 55% efficacy in preventing hospitaliza- 89,90 tion in high-risk infants Varicella zoster VZIG is efficacious even soon after exposure 91 BPIG, bacterial polysaccharide immunoglobulin; CNS, central nervous system; HBIG, hepatitis B immunoglobulin; RSV, respiratory syncytial virus;...
aTreatment options for RSV infections are still limited lnitially apolyclonal RSV antibody (RSV-IGIV,Medlmmune)was developed,it was then replaced by the newer humanized monoclonal antibody(palivizumab,Medlmmune)Palivizumab, the only FDA-approved monoclonal antibody forRSV,targets the highly conserved RSV...
This epitope, which is identical to the palivizumab epitope, was reported to confer high titers of RSV-neutralizing antibody responses [83]. Following this trend, numerous chimeric VLP studies have been conducted to date that revolved around expressing RSV antigens on different virus backbones. ...