Protein coding features can emerge de novo in non coding transcripts, resulting in emergence of new protein coding genes. Studies across many species show that a large fraction of evolutionarily novel non-coding RNAs have an antisense overlap with protei
If mutation occurs causing transcription of a gene to occur on both strands of the DNA in the same cell, what affect would you expect that to have on the production of protein for the gene?What is mutation of the DNA? Why does it happen? What can happen if there is mutation of D...
How many genes are in a somatic cell? What is the difference between cell lineage from cell growth? Explain. How do mutations lead to genetic variation? How to determine allele frequencies in a gene pool? In the context of molecular genetics, how does one reconcile the terms overlapping and...
In live-bearing animal lineages, the evolution of the placenta is predicted to create an arena for genomic conflict during pregnancy, drive patterns of male sexual selection, and increase the rate of speciation. Here we test these predictions of the vivi
For example, if certain TF binding events only occur in a fraction of cells, they will have a reduced ChIP-seq signal overall. Myth 6: Transcription factors mainly function as activators in mammalian cells Although the lac and lambda repressors were the first sequence-specific TFs that were ...
Brown Region and cyt b were both amplified via two overlapping fragments to ensure that sequences were obtained even if the DNA was degraded (as can be expected in faecal samples). To prevent amplification of nuclear pseudogenes, we used primers known to solely amplify the mitochondrial fragment...
1,2 Depending on where these clots occur, they can cause dangerous or even life-threatening complications.3 Blood clots can form in veins (venous clots), interfering with the return of blood from tissues to the heart, or arteries (arterial clots), interfering with movement of oxygenated ...
While it is usually experienced as hip pain, it routinely involves widespread pain in the low back, throughout the glutes, and down the side and back of the leg as well. It is a distinct condition in its own right, and yet it probably has more than one overlapping cause, including ...
(childhood body size). To assess whether sample overlap could have potentially led to winner’s curse bias in step 1 of MR, a split-sample analysis was performed. Results of non-overlapping samples analysis were similar to the full sample analysis, suggesting that using the same data source ...
In general, the holoenzyme dimer resembles a "U" shape, with each side constituting a monomer containing both recognition and catalytic domains with an overlapping bridging domain at the bottom. The DNA is bound between the two subunits. FokI, the most studied Type IIs enzyme, appears to exist...