DNA viruses exist in both single- and double-stranded forms with single-stranded DNA viruses often undergoing rapid mutations to become dangerous to humans and other organisms. These mutations occur because while double-stranded DNA can be checked for errors against the other strand, single-stranded...
COVID-19 is a reminder of their destructive power, but they’re crucial to humans’ development and survival.
Viral RNA integration is an intelligent and intricate mechanism that viruses have developed to ‘hijack’ the host cell’s machinery. This means that, after integration, the host cell uses the viral RNA code to produce viral proteins like it would its own proteins. Building a new virus The HI...
After the initial attachment to a host cell, viruses penetrate the membrane and release their viral genome into the cytoplasm. Subsequently, the machinery of the host cell is diverted to replicate the viral genome and translate it to viral proteins. After the assembly of the produced components ...
investigating changes to protein expression following genetic manipulation or post-translational modification (PTM), and assessing viral titers to understand how viruses replicate in different types of host cells. In-cell Westerns are also used for monitoring protein localization within specific cellular com...
1). The influenza A virus is an enveloped virus, containing a segmented genome consisting of eight single-stranded negative-sense RNAs. While most RNA viruses replicate in the cytoplasm, influenza replication takes place in the nucleus, likely due to the requirement for cellular splicing machinery ...
Masters of manipulation: how do positive-sense RNA viruses employ plant proteins to replicate, move from cell to cell, and overcome antiviral immunity?Plant host factorPlant viruses(+)RNA virusesMasters of manipulationViral replicationViral movement...
At the molecular level, viruses invade cells and manipulate them to replicate, survive, and cause disease. Since they depend on human cells for their life cycle, one-way viruses co-opt cellular machinery is through protein-protein interactions within their cell host. Similarly, cells respond to ...
How do you take molnupiravir (Largevrio) ? Molnupiravir is to be used by adults with mild to moderate COVID-19 , who have had a positive test for COVID-19 and be at risk of developing severe COVID-19 illness. Start molnupiravir as soon as possible after COVID-19 diagnosis and...
Chemists from theUniversity of Chicagohave successfully assembled a massive model of the nuclear pore complex and the HIV-1viruscapsid. Because viruses have to hijack someone else’s cell to replicate, they’ve gotten very good at it—inventing all sorts of tricks. ...