Nanoporous silica nanoparticles (NSNs) have been considered with great interest as drug delivery agents owing to their superior properties. Herein, we review typical and recent progresses of NSNs, and for the f
Nanoporous silica nanoparticles (NSNs) have been considered with great interest as drug delivery agents owing to their superior properties. Herein, we review typical and recent progresses of NSNs, and for the first time, systemically pointed out the relationship between their formation mechanism,...
or in more accurate words, to re-discover their full potential in pharmaceutical formulation. Extensive libraries of nanoparticles-that can be used for the delivery of natural bioactive compounds to a certain target-have been studied. These different nanoparticles can be designed, prepared in different...
Citation28 Among various nanotechnologies, nanoparticles (NPs) are the most extensively studied in the treatment and diagnosis of CVDs. NPs, composed of drugs and carriers, are small-sized particles known for their ease of synthesis, high tunability, and substantial drug-loading capacity. By ...
based on novel colloidal nanoparticles, which can be handled ‘in solution’ in much the same way as larger molecules. This enables researchers to apply the principles of synthetic supramolecular chemistry and the analytical tools of molecular science to control and characterise nanoscale structure with...
Nanoparticles (NPs) can offer a handful of tools to tackle these problems by enabling efficacious and safe delivery of both virus- and host-directed therapeutics. Furthermore, they can enable maximized clinical outcome while eliminating the chance of resistance to therapy by tissue-targeting and ...
Hazard and risk assessment of nanomaterials (NMs) face challenges due to, among others, the numerous existing nanoforms, discordant data and conflicting results found in the literature, and specific challenges in the application of strategies such as grouping and read-across, emphasizing the need for...
film-based nanomaterials, or plant viral nanoparticles for antigen delivery, which do not require cold chains. That day seems far off in the race to find a coronavirus vaccine that works, but it remains to be seen whether SARS-CoV-2 will be more like the flu, requiring a new shot every...
In 2022, a research team at the National Cancer Institute published their work on an innovative therapy for pleural mesothelioma using a spray-on hydrogel during surgery. The new treatment involves spraying genetically engineered nanoparticles on the cancer site to eliminate mesothelioma tumor cells left...
Lipid nanoparticles Pseudouridine Non-viral gene delivery 1. Introduction In vitro transcribed (IVT) mRNA has emerged as a powerful gene therapy platform for a wide range of therapeutic applications such as protein replacement [1,2], gene editing [3,4], vaccines [[5], [6], [7], [8], ...