Ninety-nine percent of cancer drugs never make it to tumors, getting washed out of the body before they have time to do their job. How can we better deliver life-saving drugs? Cancer researcher Joy Wolfram shares cutting-edge medical research into nanoparticles -- tiny particles that could ...
Some seem almost mundane -- nanoparticles of zinc oxide in sunblock allow you to spread a transparent lotion on your skin and remain protected. Others sound like science fiction -- doctors are attempting to use the protein casings from viruses to deliver minute amounts of drugs to treat ...
Progress is being made – just last week an example from one emerging field of research known as 'nanotherapy' hit the headlines. A UK research team found that microscopic gold bubbles – called nanoparticles – could be used to deliver a deadly drug payload and killtumourcells (albeit in the...
Most research focuses on reducing the toxicity and side effects of drugs, especially for those used in chemotherapy. Many Nanoparticles systems can be used to encapsulate the toxic drug and deliver it to specific sites in the body. These Nanoparticles are mainly made from biodegradable, biocompatible...
Newer techniques of gene therapies are being researched to develop other ways to deliver the genetic material instead of using a virus vector which can sometimes induce a severeimmune responseor cause cancer. These new techniques use extremely tiny nanoparticles to deliver the genetic material into th...
These carriers are used to package the active chemicals in drugs such as the chemotherapy Doxil or the cholesterol-lowering medicines Repatha and Praluent so they get to their targets with fewer unwanted side effects. And nanoparticles are being investigated to ferry the genome-editing CRISPR-Cas9...
The fatty envelope of lipid nanoparticles that deliver mRNA to cells also is capable of inducing toxicities, the article says. Some patients are at heightened risk of toxicity The health risks of toxicity depend to some extent on the health of the patient and how often the mRNA treatment is ...
(anti-drug antibody) responses and transient cytokines is still detectable and therefore hampering the clinical applicability of mRNA-drugs, especially when the mRNA has to be administered multiple times. Notably is also the induction of CARPA when nanoparticles are given repeatedly. This formulation ...
To distinguish colloidal silver from ionic silver, you should look for a white cloud or droplets that do not reflect light. A true ionic solution contains more than 50% silver nanoparticles. Those particles are more bioavailable and easier for the body to absorb into the body. This is why co...
for decades. Scientists in the field have developed drugs that produce some remarkable results in patients with aggressive, late-stage cancers. But most next-generation cancer immunotherapies are based on recombinant (lab-made) proteins that are difficult to deliver to specific targets in the body ...