A new study published in eLife explores how naturally occurring mutations affect the biophysical properties of nucleocapsid proteins in SARS-CoV-2. The researchers focused on the nucleocapsid protein, which is responsible for packaging and protecting the viral genome. They found that most mu...
How does sexual reproduction increase genetic mutations? How does genetic drift affect genetic diversity in a population? How do different mechanisms of evolution affect gene pool? How does reducing gene flow cause speciation? How does gene editing impact human evolution?
When genome-wide association studies emerged, scientists expected to find just a few mutations in known genes linked to a disease that would explain the difference between healthy and sick individuals. The truth, however, is much more complicated. “Sometimes, there are hundreds or thousands of mu...
How do deletion mutations affect genetic variation? How do genetic mutations influence biological diversity? How does gene flow affect diversity in a population? What is the difference between genetic drift and mutation? What is an example of genetic drift?
How do synonymous mutations affect fitness JL Parmley,LD Hurst - Wiley Subscription Services, Inc., A Wiley Company 被引量: 0发表: 2007年 Hearing silence: non-neutral evolution at synonymous sites in mammals. However, new evidence indicates that even some synonymous mutations are subject to ...
Influenza virus can escape most antibodies with single mutations. However, rare antibodies broadly neutralize many viral strains. It is unclear how easily influenza virus might escape such antibodies if there was strong pressure to do so. Here, we map all single amino-acid mutations that increase ...
this latest occurrence unveils the possibility that mink can serve as an alternate host to promote mutations of SARS-CoV-2, which can be passed back to humans and other animals, both domestic and wild and potentially placing the wild mustelid (minks, ferrets and related species) popu...
Fig. 3: Boxplots of the difference in mutation establishment rate between mutation A (originating in a low rank) and mutation B (originating in a high rank) in the four scenarios of the two mutations model. Population size in all simulations is 300. Each simulation consists of 3000 iteratio...
www.nature.com/scientificreports OPEN Unique sex chromosome systems in Ellobius: How do male XX chromosomes recombine and received: 26 February 2016 accepted: 27 June 2016 Published: 18 July 2016 undergo pachytene chromatin inactivation? Sergey Matveevsky1, Irina Bakloushinskaya2 & Oxana ...
The genes studied by DMDD are known as 'embryonic lethal', because they are so crucial to development that an embryo missing any one of them can't survive to birth. Studying these genes can help us understand how embryos develop, why some miscarry, and why some mutations can lead to abn...