coagulationhemostatic agentsHemostasis is a critical component of the preservation of hemodynamic stability and operative visibility during surgery. Initially, hemostasis is achieved via the careful application of direct pressure to allow time for the coagulation cascade to create a fibrin and platelet plug...
Other agents that do not target ITP pathogenesis, such as antifibrinolytics, recombinant activated factor VII, and oral contraceptives (for female patients with menorrhagia), can be helpful in stopping the active bleeding under certain conditions....
physical examination, complete blood count, and peripheral blood film assessment are the basic workups for suspected patients. Splenomegaly and constitutional symptoms (e.g., fever, weight loss, or lymphadenopathy) are unusual and, if present, should be investigated further ...
344,345 It is frequently used in combination with other antiplatelet agents that inhibit other platelet activation pathways and work additively or synergistically with aspirin.4 However, long-term use of aspirin, even at low doses, is associated with an increased risk of bleeding, most notably in...
contamination with some viruses and the associated transmission risk is a possibility. Regardless of this disadvantage, FM can be considered a convenient option for submucosal injection during EMR and ESD due to its reasonable price compared with other viscous agents and to its hemostatic properties[5...
Point-of-care testing will have an important role in guiding fibrinogen replacement for hemostatic therapy in clinical settings such as cardiovascular surgery, postpartum hemorrhage, and trauma. Fibrinogen therapy is an important component of a multimodal strategy for the treatment of coagulopathic ...
This work provides an overview of the most used skin repair ingredients, highlighting their different mechanisms of action, aiming to provide an up-to-date tool to support health professionals’ decisions. Keywords: skin repair; wound healing; trends; scientific evidence; epidermal barrier; metal ...
This work was supported by “UCAM-Universidad Católica San Antonio de Murcia, Grant numbers PMAFI-27/21 and PMAFI-12/21”, Murcia, Spain. Data Availability Statement Not applicable. Conflicts of Interest The authors declare no conflict of interest. References Rahmany, M.B.; Van Dyke, M....
for changes in activities, policies, and procedures at all levels of the organization. Blood operators can utilize “Plan-Do-Study-Act” cycles spanning from: vigilance for emerging viruses, surveillance activities and studies, operational continuity, donor engagement and trust, and laboratory testing ...
Although older patients are generally less sensitive to the cardiac effects of beta-blockers due to reduced beta-receptor expression, orthostatic hypotension remains a frequent ADR with these agents [62]. Older women may be at increased risk of drug toxicity, primarily due to elevated drug serum ...