Cell death is important for maintaining cell number and preventing aberrant cell growth, which leads to cancer. There are three mechanisms of cell death: necrosis, asutophagy and apoptosis.Answer and Explanation: CTL and NK cells induce apoptosis through the Fas mediated signalling pathway....
Cells depend on specific stimuli, such as trophic factors, for survival and in the absence of such stimuli, undergo apoptosis. How do cells initiate apoptosis in response to the withdrawal of trophic factors or other dependent stimuli? Recent studies of apoptosis induction by neurotrophin withdrawal...
Do memory cells undergo apoptosis? During the primary immune response, memory cells do not respond to antigens and do not contribute to host defenses. As the infection is cleared and pathogenic stimuli subside, the effectors are no longer needed, and theyundergo apoptosis. ... As a result, m...
How do CTL and NK cells cause other cells to undergo apoptosis? How is compartmentalization and specialization within cells more energetically efficient? Discuss how CatSper channels are activated and what Ca^{2+} does once it enters into the cell. ...
This nuclear protein stays contained within the nucleus during apoptosis, but is released when cells undergo necrosis (Raucci et al., 2007). Currently, this is typically done by analyzing the supernatant for HMGB1, or by microscopy. This would be an excellent assay to implement on a tool like...
For example, chronic lymphocytic leukemia cells survive well in a lymph-node niche in vivo but rapidly undergo apoptosis ex vivo. This indicates that (i) the downstream apoptosis machinery is usually functional in these cells, and, that (ii) they are ready-to-die and as such strictly ...
Cartilage cells undergo apoptosis, leaving large cavities in the matrix, and the matrix itself becomes mineralized by the deposition of calcium phosphate crystals by osteoblasts. Osteoclasts and blood vessels invade the cavities and erode the remaining cartilage matrix, creating a space for the bone ...
For example, chronic lymphocytic leukemia cells survive well in a lymph-node niche in vivo but rapidly undergo apoptosis ex vivo. This indicates that (i) the downstream apoptosis machinery is usually functional in these cells, and, that (ii) they are ready-to-die and as such strictly ...
Are killer T-cells memory cells? How are hybridoma cells produced? Describe how T-cells and B-cells play its role in specific immunity? Why are cells limited in the size to which they can grow? How are meristem cells modified? What cytokine causes abnormal cells to undergo apoptosis? What...
Why does a cell undergo mitosis? How does mitosis in animal cells differ from mitosis in higher plant cells? How are proteins transported out of a cell? What role do cofactors play in cell signaling? How does mycoplasma spread in cell culture?