The seasonal flu vaccine will not provide protection from swine flu, but numerous drug companies are furiously at work on a swine flu vaccine that is expected to be available in the fall of 2009. As with the antivirals, doctors may need to prioritize who receives the vaccine at first. In...
There are two ways of treating viral infections. One is to find small molecules that stop viruses replicating by interfering with viral proteins. Antivirals are usually simple to manufacture, and can be taken in pill form, both big advantages. But 99 per cent of potential smal...
He said foxes and otters are known to scavenge, and it's likely the bird carcasses would have had high viral loads. "Such high exposure is likely to have overwhelmed the mammal's immune system, resulting in infection," he said. Do we need to worry about bird flu spreading ...
The seasonal flu vaccine will not provide protection from swine flu, but numerous drug companies are furiously at work on a swine flu vaccine that is expected to be available in the fall of 2009. As with the antivirals, doctors may need to prioritize who receives the vaccine at first. In...
Antiviral and immunomodulatory therapy Interferon has been used to treat hepatitis B for almost 50 years; however, its exact mechanisms of action are still unclear. While IFN has a less potent inhibitory effect on HBV DNA replication compared to NUCs, it results in higher rates of HBeAg and HB...
Others: Vitamin A for severe measles [31] Supportive Antivirals: Rifampin: For RSV myocarditis [36] Pleconaril: severe Enterovirus infections Oseltamivir: Severe influenza ART: HIV-1 Corticosteroids: do not reduce mortality (data based on small RCT of poor quality) [37] Immunotherapies: IVIG (...
What are mRNA vaccines, and how do they work? Repurposing antivirals Until recently, there were very few effective antivirals, said Stephen Morse, a professor at Columbia University's Mailman School of Public Health. That was especially true for RNA viruses — like 2019-nCov andHIV— which us...
However, the model here suggests mammalian temperature may be a constraint on HIV binding (due to the large negative ΔCp and ΔSa_immob) in effect exposing a potential weakness in the HIV infection process which could be exploited for antiviral therapy. The implications of making ΔSa_im...
Genetic Resistance to Drugs:Engineered resistance to all known antibiotics, antivirals, and other antimicrobial treatments, rendering existing medical interventions ineffective. Immunity to Vaccines:The ability to evade or suppress the immune response triggered by vaccines, rendering vaccination efforts useless...
Others: Vitamin A for severe measles [31] Supportive Antivirals: Rifampin: For RSV myocarditis [36] Pleconaril: severe Enterovirus infections Oseltamivir: Severe influenza ART: HIV-1 Corticosteroids: do not reduce mortality (data based on small RCT of poor quality) [37] Immunotherapies: IVIG (...