The structures suggest that the T-loops do not have a rigid structure and that they may be flexible in solution. The presence of a turn of 310 helix in the middle of the T-loop suggests that secondary structure could form when it interacts with soluble receptor enzymes. Co-crystals of G...
In this method,structuresaredeterminedfromdiffractionpatternsgenerated from well-ordered three-dimensional(3D) crystals ofbiological macromolecules. Theresolutionsofstructuresdetermineddependlargelyonthe quality ofthe crystals;inshort,obtainingwell-ordered3Dcrystalsofsufficientsizeisusuallya prerequisite for atomic ...
By mixing borax with hot water and allowing it to cool, kids can observe the formation of intricate and beautiful crystal structures. This experiment is an excellent illustration of how temperature changes affect the solubility of substances. Luckily, you don’t need expensive or unique supplies to...
Among the physicochemical cues in the cellular microenvironment that orchestrate cell processes, the different levels of curvature in the extracellular matrix and intrinsic to the tissues play a pivotal role in the spatiotemporal control of key cellular
Two completely flexible random chains containing N atoms joined by links of length L can be superimposed by rigid-body motions to match their structures as closely as possible. The statistics of the root-mean-square best-fit distance D are discussed. For long chains, D2 tends of 0.125L2N. ...
The crystal structures of hundreds of thousands of molecular compounds have now been determined with the quantitative information being stored in large databases. Chemists are generally interested in that specific part of this information which refers to individual molecules. The packing of ...
Since filaments are not present in the periacrosomal region during the accumulation of the actin even though the fixation of these cells is sufficiently good to distinguish actin filaments in thin section, the actin must accumulate in the nonfilamentous state. The membranes in the periacrosomal ...
If the second immiscible fluid did not preferentially wet the particles, it would agglomerate the particles and create sample- spanning network structures due to the strong capillary forces from the bulk wetting fluid. In contrast to the pendular state, this is called capillary state11,13. The ...
How Are Heat and Temperature Related? You have seen how temperature relates to heat. But how was the size of "one degree" determined in the first place? People had to have a way of marking the spots on the temperature scale between "frozen" and "boiled away" and assigning numbers to th...
rotations. In particular, the bulk halide perovskite such as CsPbBr3, which possesses one of the simplest halide perovskite structures, is a good benchmark system to understand the fundamental physical mechanisms but already presents several outstanding questions. First, what is the intrinsicτsof ...