Like other species, we are the products of millions of years of adaptation. Now we're taking matters into our own hands.
The specific activity of enzymes can be altered over long timescales in cells by synonymous mutations that alter a messenger RNA molecule’s sequence but not the encoded protein’s primary structure. How this happens at the molecular level is unknown. He
What would the genotype ratio of the offspring be for two individuals that are heterozygous? How many chromosomes are in a sex cell? How many sexual genetic mutations are there? If 80 offspring come from the cross AaBB \times aaBb, how many of them will have the genotype AaBb?
The earliest patients have begun receiving the first approved medical treatment created with the genomic scissors, a gene therapy for sickle-cell disease—and a growing list of foods created with CRISPR are slowly reaching grocery store shelves. Many more CRISPR-edited plants...
// array is cloned in order to allow mutations // in `fn` but not suffer from them, so iteration // keeps normally. array = Array.prototype.slice.call(array,0); for(var i = 0, len = array.length; i < len; i++) { fn.call(scope, array, i, array); ...
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How to make consistent backup of whole ClickHouse database, with assumption that we are using ALTER ... DELETE/UPDATE operations. TomaszUrugOlszewski changed the title Shadow not consistent during mutations Question - How to make consistent backup with FREEZE during mutations Jan 10, 2019 alexey-...
In the last 20 years, investigators have identified mutations with a founder effect, but also a series of private variants. Multi-component models have been developed to understand if a variant is deleterious or neutral. However, these models are not sufficient to understand the roles of UVs. ...
(SEDAR) approved a project by Ubikare, a bioengineering group, and scientists from 80 centers across Spain [55]. The company created “Reg Covid-19” statistical tool to provide healthcare professionals, access to datasets of coronavirus infected patients and insights on disease progression, ...
An association between the basal subtype and germline mutations in the BRCA1 gene, often termed the “caretaker of the genome”, has been well described, and it may be speculated that both inherent DNA damage–sensing processes and DNA repair mechanisms are central in the development of basal-...