The actions of regulatory T cells constitute one mechanism of peripheral tolerance. Type 1 diabetes A chronic autoimmune disease that is characterized by the T-cell-mediated destruction of β-cells (which secret
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How Are the Patient Populations Characterized in Studies Investigating Depression in Advanced Cancer? Results From a Systematic Literature Review. J Pain Symptom Manage 2014; 48(4): 678-98. doi: 10.1016/j.jpainsymman.2013.11.013Janberidze E, Hjermstad MJ, Faksvg- Haugen D. How are the ...
facilitate the dynamic reorganization of the actin cytoskeleton, which in turn allows cancer cells to establish cellular protrusions that are crucial for their interaction with the extracellular matrix and movement. This interaction is particularly crucial for the cells' capacity to degrade barriers, whic...
Cancers are a group of related diseases characterized by the uncontrolled division of abnormal cells. While normally cells experience a natural process of division, growth, and death, cancer cells survive and interrupts this process. This can result in congregations of cancer cells called tumors that...
Epithelioid cells are the most common mesothelioma cell type. Epithelioid mesothelioma cells are characterized by a single nucleus, a rectangular shape, and slow growth. Oncologists (cancer doctors) also refer to this cell type as epithelial mesothelioma. With epithelioid mesothelioma, the tumor cells...
The precise connection between global hypo - methylation and the expansion of cancer stays to be fixed. Anomalously, in conjunction with global hypo-methylation, the genomes of cancer cells are as well specified by localized parts of the novo hyper-methylation, usually in the CpG island of tumor...
While the team tested BENEIN using colorectal cancer cells, they think its use could extend to other cancers and even to other cellular diseases. “The applications of BENEIN extend beyond cancer reversion. By identifying key regulators of cell state transitions, BENEIN holds potential for broad...
Apoptosis has been established as a mechanism of anti-cancer defense. Members of the BCL-2 family are critical mediators of apoptotic cell death in health and disease, often found to be deregulated in cancer and believed to lead to the survival of malign
Early lesions known as fatty streaks are characterized by cholesteryl ester-laden ‘foam cells’, which accumulate owing to unregulated uptake of native and modified lipoproteins, predominantly by macrophages and VSMCs. More-advanced lesions contain a core region of activated immune cells, cholesterol ...