Researchers from the Wellcome Sanger Institute and their collaborators focused on the ‘cancer protection’ gene RAD51C, known to increase ovarian cancer risk six-fold and risk of aggressive subtypes of breast cancer four-fold. They found over 3,000 harmful genetic changes that could potentially di...
Breast cancerHER2PathologyTumour markersHuman epidermal growth factor receptor 2 (HER2) is overexpressed, usually as a result of HER2 proto-oncogene amplification, in 20鈥 30% of breast cancers. A HER2-positive status is generally associated with more aggressive disease and a worse prognosis. ...
The argument for aggressive screening for breast cancer [1:22:15]; Advances in the treatment of breast cancer, adjuvant therapy, and neoadjuvant therapy [1:27:00]; The use of hormone replacement therapy in women who are in remission from breast cancer [1:41:15]; ...
How does thyroid cancer spread? How does papillary thyroid cancer spread? What is the survival rate for thyroid cancer? What is follicular thyroid cancer? What is the survival rate for stage 4 thyroid cancer? How aggressive is thyroid cancer?
Rapid Translation of a Novel and Potent Vaccine in HER2+ Metastatic Breast Cancer Patients Principal Investigator: Kim Lyerly, MD, Duke Medical Center Approximately 20 percent of breast cancers are HER2+, meaning they over-express the HER2 gene, resulting in a particularly aggressive form of th...
subsequent tests, Tookes learned she had HER2 breast cancer, an especially aggressive form that can be difficult to treat. Though her doctors caught the cancer early, they wanted to be certain it would never return, which meant a unilateralmastectomyfollowed by 12 rounds of punishing chemotherapy....
breastcancer," said Sandra Martha Gomes Dias, a cancer researcher at the Brazilian Biosciences National Laboratory in Campinas, Brazil. "TNBC is considered to be more aggressive and have a poorer prognosis than other types of breast cancer, mainly because there are fewer targeted medicines that ...
1., 2. Although it is generally more chemosensitive than other types of breast cancer, it is also characterised to harbour the most aggressive behaviour with the front-loaded risk of relapse within the first 3–5 years after completion of adjuvant chemotherapy and its prevalence in younger ...
“Metastatic castration-resistant prostate cancer is the most advanced and aggressive stage of the disease, and the TALAPRO-2 results provide much-needed hope to patients who remain in high unmet need of effective treatment options.” PT886 and Pembrolizumab Trial Commences for Gastric and GEJ ...
Inflammatory breast cancer (IBC) is an uncommon and aggressive presentation of locally advanced breast cancer that is potentially curable when localized but may be associated with distant metastasis in up to one-third of patients at presentation. The diagnosis of IBC is made based on clinical ...