Housing in the MDS determined a strong up-regulation of activity and feeding behaviour and a concomitant decrease in inactivity. Importantly, housing in the MDS disrupted circadian rhythmicity in mice and also determined a decrease in body weight. Finally, when mice were tested in the EPM a ...
Imputation of missing scale scores was performed by multiple imputation [42] using the R package mice [43], applying the predictor matrix quickpred (mincor = 0.3) and performing m = 5 iterations. Mixed-effects models for repeated measures were conducted with the multiply imputed ...
Comprehensive searches (via Ovid, CABI, Web of Science, Proquest and SCOPUS on May 24 2020) yielded 10,094 publications. Screening for inclusion criteria (published in English, using mice or rats and providing ‘enrichments’ in long-term housing) yielded 214 studies (within 165 articles, using...
In laboratory animal facilities, it is a common code of practice to house female mice in groups. However, some experimental conditions require to house them individually, even though social isolation may impair their well-being. Therefore, we introduced a separated pair housing system and investigate...
Lifetime breeding studies in fully fed and dietary restricted female CFY Sprague-Dawley rats. 1. Effect of age, housing conditions and diet on fecundity. Mech. Ageing Dev. 33: 19–28 (1985). Article CAS PubMed Google Scholar Finn, C.A. Reproductive capacity and litter size in mice: ...
Cipollone D, Carsetti R, Tagliani A, Rosado MM, Borgiani P, Novelli G, D'Amati G, Fumagalli L, Marino B, Businaro R: Folic acid and methionine in the prevention of teratogen-induced congenital defects in mice. Cardiovasc Pathol. 2009, 18 (2): 100-109. 10.1016/j.carpath.2008.02.007...
not eating. This consistency of timing of the estimated BMR implies that our pragmatic definition of BMR is of biological relevance. Importantly, we found that when we divided the daily mean energy expenditure (MEE) of the mice at 30 °C with the BMR defined in this way, we obtained a ra...
Furthermore, L-selectin expression may not be necessary to maintain leukocyte rolling as platelets have been reported to re-establish leukocyte trafficking in CD62L deficient mice [47]. It is clear that a number of genes involved in integrin binding are up-regulated in weaned calves and that,...
Because the genome of mice has evolved in an environment that includes all enrichment aspects used in environmental enrichment experiments (e.g., exercise, social interaction, ability to build nest, relatively larger space for exploration), we consider environmental enrichment as the baseline housing ...
In the present study, we aimed to assess affective states of individually and pair-housed calves on a spatial Go/No-go task design with active trial initiation. To this end, we adapted to dairy calves the task design developed and successfully used in mice, rats and horses by Hintzeet al...