Since (almost) all body cells inherit the same genetic information we might ask why they aren’t all identical to one another. In general the reason is to do with the way in which the different parts of the genetic information are used (or not used) in different cells. When we study...
Hereditary equine regional dermal asthenia (HERDA) results from a genetic mutation which affects the skin and other tissues of Quarter Horses and horses with Quarter Horse lineage. The disease HERDA has an autosomal recessive mode of inheritance and has become a significant concern in the Quarter ...
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Horses that possess the underlying mutation (a duplication of STX17) responsible for this colour pattern also possess a higher incidence of melanoma [39]. In mice, as in other animals, the agouti protein affects pigmentation. This gene normally produces black hair by interfering with the ability...
Are they up to date on immunizations, coggins, teeth float, deworming and farrier. List details of how your curly has been used in the past. Be specific and thorough. Is he/she good with traffic, dogs, crossing water, bridges, an anything else? Are they registered? DNA? Genetic testin...
"Roan" refers to a horse coat color pattern characterized by a mixture of colored and white hairs on the body, while the head and "points"—lower legs, mane and tail—are mostly solid-colored. Horses with roan coats have white hairs evenly intermingled throughout any other color. The head...
genetic testing for a limited number of inherited equine diseases (seeTable 27-1). For autosomal recessive conditions, one breeding strategy is to avoid carrier-to-carrier matings. This will eliminate affected animals from the population, but it will not eliminate the deleterious mutation from the...
Genetic diversity and population structure First, we performed a PCA on the LD pruned subset of SNPs using the “prcomp” function (with scale = TRUE) of the R statistical software (R Core Team2013). Then, we used the first three PCs to identify and remove outlier samples, as possibly th...
There is a genetic reason why some horses have the ability to gait while others do not, and that is because some are gifted with a gene mutation nicknamed the “gait keeper”. Its real name is the less fun, DMRT3. In mice, the DMRT3 gene plays a role in the development of limb mo...
59–61 The DMRT3 mutation in several breeds, including the Standardbred, has surfaced as something to be considered relative to racing success. The AA genotype of DMRT3 is better for racing success, while horses with CC or CA genotypes are better for general riding.60,62 MSTN, the ...