SEXUAL DIFFERENTIATION OF PITUITARY FUNCTION The role of the ovarian steroids in the negative feedback inhibition of gonadotropin secretion was examined in rhesus monkeys which were ovariectomized and simultaneously implanted s.c. with Silastic capsules containing either estradiol ... FJ Karsch,DJ Diersch...
Urinary testosterone concentration (ng/dL) as a function of age (d). Plotted points are individual sample values, and those connected by line segments represent multiple visits by the same infant. Plotted nonlinear trajectories were fitted using generalized mixed model for individual sample values (...
The Role of Sex Hormones and the Tissue Environment in Immune Protection Against HIV in the Female Reproductive Tract Despite extensive studies of the mucosal immune system in the female reproductive tract (FRT) and its regulation by sex hormones, relatively little attenti... CR Wira,M Rodriguez-...
Many of the immunological effects of testosterone are due to its conversion to estradiol by aromatase in the thymus and in other lymphoid organs. The adrenal androgen, dehydroepiandrosterone stimulates immune reactions in experimental animals and in man. It antagonizes the immunosuppressive effect of ...
a"In particular, fat in the liver interferes with its function and insulin sensitivity," Katz said. This starts a domino effect, he explained. "Insensitivity to insulin causes the pancreas to compensate by raising insulin output. Higher insulin levels affect other hormones in a cascade that ...
Genetic and pharmacological manipulations of the serotonergic system in early life: neurodevelopmental underpinnings of autism-related behavior Serotonin, in its function as neurotransmitter, is well-known for its role in depression, autism and other neuropsychiatric disorders, however, less known ... K ...
The NERP-4–SNAT2 axis regulates pancreatic β-cell maintenance and function Amino acids modulate insulin secretion via amino acid transporters expressed on β cells. Here, the authors show a VGF-derived peptide NERP-4 acts as a positive allosteric modulator on the amino acid transporter SNAT2...
The brain is an integral component of the reproductive system since the secretory activity of the pituitary and thus gonadal function are under its control... RA Gorski,CD Jacobson - Springer Netherlands 被引量: 548发表: 1981年 Sexual Differentiation of the Brain This chapter discusses the sexual...
Function of the endocrine system Glands and hormones of the human endocrine system Growth and development Endocrine-related developmental disorders Ectopic hormone and polyglandular disorders Endocrine changes with aging References & Edit HistoryRelated Topics ...
There are good clues from the clinic and laboratory that are revealing. One clue is the close link between organ-specific cytokine production during the normal menses, pregnancy, and immune function. Changes occur at the cellular level in animals and cell culture in response to sex steroids. ...