and significant associations with a history of suspected miscarriage, maternal coagulation factors gene mutations, and reduced protein S or protein C activity.#Our data confirmed a high incidence of cerebral ab
Hermans M, Gala JL, Buysschaert M (2006) The MTHFR C677T polymorphism confers a high risk for stroke in both homozygous and heterozygous T allele carriers with Type 2 diabetes. Diabetic medicine 23: 529-536.Hermans M, Gala JL, Buysschaert M (2006) The MTHFR C677T polymorphism confers ...
The gene for methylenetetrahydrofolate reductase (MTHFR) has shown polymorphism in the general human population. In its homozygous form, a C677T mutation occurs in more than 5% of the grown-up population and produces a thermolabile variant which reduces the overall enzyme activity to less than ...
The presence of an MTHFR C677T homozygous polymorphism was defined as exposure. Risk factors for endometriosis were considered confounders in a binomial logistic regression, with endometriosis diagnosis as the dependent variable. Among the 409 included patients, 106 (25.9%) cases and 303 (74.1%) ...
The analysis of MTHFR polymorphism distribution according to endometriosis diagnosis showed a lower rate of MTHFR wild-type (22.6% vs. 39.9%, p = 0.0014) and a higher rate of MTHFR C677T homozygous polymorphism—A1298C wild-type in patients with endometriosis (24.5% vs. 15.8%, p = 0.0453...