Developmental biology: Homeobox genes: eyeing the clockdoi:10.1038/nrg1996PentimalliFrancesca
In early embryogenesis, both genes were expressed as the same pattern at a region where the shoot apical meristem would develop later. In late ... Y Sato,N Sentoku,Y Nagato,... - 《Plant Molecular Biology》 被引量: 119发表: 1998年 Abnormal cell divisions in leaf primordia caused by the...
The regulation ofHoxgene expression is complex. A major regulator along parts of the anteroposterior axis of the developing central nervous system isretinoic acid, but this effect is mediated by other genes. At a different level,Hoxexpression is influenced by modifications of chromatin and the three...
These experiments describe for the first time regulation of the Delta-Notch pathway by MSX1, and connect these genes to the PHOX2B oncogene, indicative of a role in neuroblastoma biology. Affymetrix micro-array analysis of a neuroblastic tumour series consisting of neuroblastomas and the more ...
Human congenital birth defects as well as phenotypes of mice mutants demonstrate that many genes have functions in the development of both the craniofacial and the limb skeleton. We focus on a subgroup of aristaless-related genes (a structurally defined family of homeobox genes) that share such ...
Homeobox genes and axial patterning. Cell 68, 283–302 (1992). Article CAS Google Scholar Duboule, D. Temporal collinearity and the phylotypic progression: a basis for the stability of a vertebrate Bauplan and the evolution of morphologies through heterochrony. Development Suppl. 135–142 (1994...
2005, Current Topics in Developmental Biology Citation Excerpt : Secondary androgen‐response genes are commonly defined using two criteria: (1) delayed induction after androgen treatment; and (2) lack of discernible AREs in their promoters. The first criterion can give false positives; as an exampl...
摘要: Homeobox (HOX) transcription factors are important for the regulation of normal hematopoiesis. Many cases of acute myeloid leukemia (AML) are driven by aberrant expression of clustered HOX genes that is mediated by chimeric oncoproteins involving MLL, chromosomal translocations directly affecting...
We then applied RNAi in both male and female one-day-old pupae to study functions of the six upregulated homeobox genes:AlAbd-B, AlAntp(ANTP-HOXL family),AlUnc-4,AlShox2,AlRepo(PRD family), andAlAp2(LIM family). In addition, we studied functions of two genes,AlAbd-AandAlUbx(ANTP...
genes.127,128,131It is unknown whether lung disease results primarily through the reduction of one surfactant component (such as SP-B or ABCA3) below a critical level needed for normal lung function or a combination of reduced levels of more than one protein. Surfactant protein expression has ...