Conclusion: This study confirms that the safety and effectiveness of Holmium-166 SIRT derived from prospective trials also applies in routine clinical practice, reinforcing its potential as a viable treatment option for primary and secondary liver cancer.Schulze-Zachau, Victor...
selective internal radiation therapy (SIRT)holmiumsafetyBackground: Transarterial radioembolization (TARE) is used to treat primary and secondary malignancies in the liver that are not amenable to curative resection. Accumulating evidence demonstrates the efficacy and safety of TARE with ...
dosimetryholmium platformTARESIRTTransarterial radioembolization (TARE) with 166Ho-loaded microspheres is an established locoregional treatment for hepatocellular carcinoma (HCC), introduced in 2010. This study evaluates the clinical outcome of patients with HCC who underwent 166Ho-TARE with personalized ...
RadioembolizationSIRTLiverHepatocellular carcinomaHCCRadioembolization-induced liver diseaseREILDRILDPurpose To investigate clinical feasibility, technical success and toxicity of 166Ho-radioembolization (166Ho-RE) as new approach for treatment of hepatocellular carcinomas (HCC) and to assess......
SIRTHolmiumEmbolisation, therapeuticTechnetium Tc-99m Aggregated AlbuminRadioembolisation is generally preceded by a scout dose of technetium-99m-macroaggregated albumin to estimate extrahepatic shunting of activity. Holmium-166 microspheres can be used as a scout dose (±250 MBq) and as a ...
radioembolizationSIRTTAREPurposeDrescher, RobertSeifert, PhilippGuehne, FalkAschenbach, ReneKuehnel, ChristianFreesmeyer, MartinJena Univ Hosp Clin Nucl Med Klinikum 1 D-07747 Jena GermanyJournal of endovascular therapy: an official journal of the International Society of Endovascular Specialists...
SIRTHolmiumEmbolisationtherapeuticTechnetium Tc-99m Aggregated AlbuminRadioembolisation is generally preceded by a scout dose of technetium-99m-macroaggregated albumin to estimate extrahepatic shunting of activity. Holmium-166 microspheres can be used as a scout dose (+/- 250 MBq) and as a therapeutic...
SIRTHolmiumImage-guidedPersonalizationDosimetryClinicaltrials.gov, identifier NCT04269499, registered on February 13, 2020 (retrospectively registered).doi:10.1007/s00259-022-05902-wRoosen, JoeyWestlund Gotby, Lovisa E. L.Arntz, Mark J.Fütterer, Jurgen J....
SIRTLiverHolmiumImage-guidedPersonalisationTreatment deliveryTo develop and validate a novel administration device for holmium-166 transarterial radioembolisation (TARE) with the purpose of facilitating controlled fractional microsphere administration for a more flexible and image-guided TARE procedure.#A ...