该HNRNPK Polyclonal Antibody. This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are
Additionally, the N6-methyladenosine (m6A) modification was mediated by N6-adenosine-methyltransferase 70-kDa subunit (METTL3) and recognized by insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1)/IGF2BP3, which maintained lnc-CTHCC stability and increased its expression in HCC. ...
macromolecular synthesis, and redox balance. Recent studies have provided profound insights into the pivotal role of the TCA cycle in cancer metabolism, suggesting that it is a promising focal point for cancer therapy [26,27,28]. IDH2 is an essential rate-limiting enzyme in the TCA cycle that...
Additionally, theN6-methyladenosine (m6A) modification was mediated byN6-adenosine-methyltransferase 70-kDa subunit (METTL3) and recognized by insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1)/IGF2BP3, which maintained lnc-CTHCC stability and increased its expression in HCC. Together,...
此外,RNA-seq数据的GSEA表明,SDCBP2-AS1的敲低与β-连环蛋白的过表达呈正相关(图5B)。lncRNA的亚细胞定位与功能。SDCBP2-AS1主要位于细胞质中,与β连环蛋白表达相关,提示SDCBP2-AS1干扰β连环蛋白的降解。为了确认,蛋白质免疫印迹分析...