pylori-associated chronic gastritis and intestinal metaplasia, which was reduced after eradication of the organism (median score 2 vs. 1, P = 0.037 in chronic gastritis; median score 2 vs. 0, P = 0.008 in intestinal metaplasia). While the normal gastric mucosa showed strong p27 expression, ...
Currently, there is no cure for Lynch syndrome. Patients with Lynch syndrome should undergo lifelong cancer screening beginning in adulthood. 目前为止,林奇综合征无法治愈,需要终身癌症筛查。另外,阿司匹林可能有一定的作用来预防减少其发生癌症的风险,但确切的剂量不甚明确。 What is Lynch syndrome?何为林奇综...
After evaluation of the family history, diagnostic microsatellite instability (MSI) analysis has found its place as a valuable screening tool for HNPCC. Immunohistochemical analysis can help to pinpoint the affected gene. The detection of a mutation in one of the responsible mismatch repair gene ...
全部,遗传性非息肉病性大肠癌,遗传性非息肉性结直肠癌 更多例句筛选 1. Conclusion A certain number of HNPCC families can be benefited from the genetic screening for mutation of the mismatch repair genes. 结论错配修复基因的突变筛选可帮助、指导临床对HNPCC家系进行严密监控。 www.120online.org 2. Objec...
Screening for the Lynch syndrome (hereditary nonpolyposis colorectal cancer) N Engl J Med, 352 (18) (2005), pp. 1851-1860 Google Scholar 18 G.J. Hollands, et al. The impact of communicating genetic risks of disease on risk-reducing health behaviour: systematic review with meta-analysis BMJ...
10. What is the appropriate screening protocol in Lynch syndrome?[J].Kleibeuker JH;Vasen HF;Nagengast FM;Cats A;van-de-Meeberg PC;de-Jong AE;Griffioen G;van-Wijk HJ,Familial Cancer.2006,第4期 上一页 1 2 下一页 相似文献 中文文献 外文文献 专利 1. 子宫内膜癌MMR蛋白检测在筛选HNP...
1. 遗传性非息肉病性结直肠癌(hereditary non-polyposis colorectal cancer) 有遗传性非息肉病性结直肠癌(HNPCC)家族史的患者需接受特殊的筛查和监测。HNPCC是常染色体显性遗传的癌症综合征,是… gck.aliyiyao.com|基于247个网页 2. 遗传性非息肉病性大肠癌 ...
Hereditary non-polyposis colon cancer is caused by mutations in DNA mismatch repair genes. The mutation spectrum in the Israeli population is poorly documented except for the c.1906G>C Ashkenazi founder mutation in the hMSH2 gene. To report our experience in HNPCC screening, the mutations detected...
Hereditary non-polyposis colon cancer is caused by mutations in DNA mismatch repair genes. The mutation spectrum in the Israelipopulation is poorly documented except for the c.1906G>C Ashkenazi founder mutation in the hMSH2 gene. To report our experiencein HNPCC screening, the mutations detected ...
sis indicatedtllatthe豫R’0fIHCWaS0.921anddiagnostic ORWaft134.290.MIS screening methodwere0.852and33.15re- spectively.withSROCmethodtofitline.ConclusionIHC.MSICanbeusedin diagnosis ofHNPCCforthe accuracy ofthemis 900denough,andrealizedianosticmetaanalysisinthe applicmion researchofHNPCCdiagnosticscreening...