在继发性HLH中,恶性肿瘤是重要病因之一,多见于血液系统肿瘤,其中又以淋巴瘤最为常见。在淋巴瘤诊疗过程中发生的HLH统称为淋巴瘤相关HLH(Lymphoma associated HLH,L-HLH)[1],未经及时诊断及治疗的L-HLH,中位生存时间低于2个月[2]。为此医学界特别邀请...
[5] SEHN L H, HERTZBERG M, OPAT S, et al. Polatuzumab Vedotin Plus Bendamustine and Rituximab in Relapsed/Refractory Diffuse Large B-Cell Lymphoma (R/R DLBCL): Final Results of a Phase Ib/II Randomized Study an...
Introduction Sub-cutaneous panniculitis T-cell lymphomas (SPTCL), a rare non-Hodgkin lymphoma, can be associated with hemophagocytic lymphohistiocytosis (HLH), a life-threatening activation of the immune system which adversely impacts su... DA Khuong-Quang,T Gayden,F Sepulveda,... - 《Blood the...
BACKGROUNDThe recent recognition of the association of Epstein-Barr virus (EBV) with T-cell/natural killer cell (T/NK-cell) lymphoma has documented that pa... T Ohno,N Miyake,S Hada,... - 《Cancer》 被引量: 65发表: 1998年 Clonal change of infiltrating T-cells in children with familia...
HLH with subcutaneous panniculitis-like T-cell lymphoma recovered well. Conclusion HLH remains a life-threatening disorder associated with a variety of underlying illnesses as highlighted by our case series.doi:10.1111/ijlh.13626Akriti GeraAROONIMA MISRA...
15.Clinical Study on 20 Cases of T-cell Lymphoma Associated Hemophagocytic Syndromes(LAHS);T细胞淋巴瘤合并噬血细胞综合症20例临床分析 16.Clinical Features and Perforin A91V Gene Analysis of So-JIA Children with Macrophage Activation SyndromeSo-JIA并巨噬细胞活化综合征临床特征及穿孔素A91V基因分析(英文...
However, four out of 15 additional individuals diagnosed with melanoma and B-cell lymphoma during their lifetime expressed either PRF1A91V or the rare pathogenic PRF1R28C variant (p = 0.04), and developed melanoma relatively early in life. Both PRF1A91V- and PRF1R28C-expressing lymphocytes ...
Umbilical cord blood transplantation induces a durable remission in hepatosplenic gamma-delta T cell lymphoma with associated hemophagocytic lymphohistiocytosis Umbilical cord blood transplantation is an alternative for hematopoietic cell allografting when Human Leukocyte Antigen compatible siblings or unrelated don...
sHLH is most commonly associated with haematological malignancies, such as T cell and NK-cell leukaemia, diffuse large B-cell lymphoma and Hodgkin lymphoma [7]. Here, sHLH is likely driven by the malignant pro-inflammatory state, but contemporaneous Epstein–Barr virus (EBV), can be a contrib...
CELL TRANSPLANTATION 25 Suggestion for SCT regimen 25 DRUG INFORMATION AND TOXICITY 27 Therapy modifications 27 DATA COLLECTION AND EVALUATION 28 BIOLOGICAL STUDIES 28 Genetic and expression studies 29 NK cell and cytotoxic T cell activity studies 29 PUBLICATION 29 REFERENCES 30 APPENDIX (copy the ...