·临床报道·HLH-2004方案治疗成人噬血细胞综合征一例徐晓度,吴冰,徐政永,王磊,陆泳萍,方奕奇作者单位:215009江苏省苏州市中医医院血液科【摘要】通过分析通过1例成人噬血细胞综合征的病史、临床表现、实验室资料及治疗过程,提高对该病的认识。【关键词】淋巴组织细胞增多症,嗜血细胞性;病例报告;诊断;治疗【中图分类...
doi:10.1182/blood-2024-207604Introduction Hemophagocytic lymphohistiocytosis (HLH) is a rapidly progressive lymphoproliferative disorder that results in excessive immune activation. Epstein-Barr virus (EBV) is associated with lymphoproliferative disorders that can range from relatively benign illnesses to ...
fromblood samples,thecodingregionsofGDF9were amplifiedusingpolymerase chain reaction(PCR)with 3 pair of palmers.Heteroduplexes相关精品文档 更多 转录因子TCF1在病毒特异性T细胞免疫应答中的作用及机制研究 肝脏特异性转录因子的功能研究 内胚层器官特异性发育因子 种子发育中的组织特异性基因表达 成骨细胞特异性转...
Fig. 1. Wright-Giemsa stains illustrating (A) macrophage (yellow circle) with red blood cells (red arrow) in the cytoplasm, consistent with hemophagocytosis; (B) budding yeast forms (yellow circle) characteristic of Histoplasma capsulatum. Table 1. Diagnostic criteria for HLH [3]. 1. Fever ...
One patient received peripheral blood instead of bone marrow because the donor was declared unfit for marrow donation. Table 1. Patient, disease and transplant characteristics Empty CellPrimary diseaseAll diseases, n (%)* HLH, n (%)*Other PID, n (%)* Age, y <1 13 (38) 1 (8) 14 ...
3.Lower serum cholesterol, soften the blood vessel, prevent arteriosclerosis; 4.It also used by the Chinese to treat dandruff and stimulate hair growth.Application(1). In food field, can be used as food additives to make tea and produce beverages, which rich in vitamin C; ...
The results of the blood analysis suggested the diagnosis of HLH. Genetic test based on high throughput amplicon sequencing was then conducted by targeting all six known HLH-causing genes simultaneously. It took only one single day to accomplish the amplicon sequencing library preparation, sequencing ...
Our results confirm that sIL-2r is a sensitive test and should be used, as per the HLH-2004 diagnostic criteria, in combination with other diagnostic tests and clinical expertise to diagnose HLH. The threshold of sIL-2r of at least 2400 U/mL used in HLH-2004 was 100% sensitive but ...
In addition, 18 patients started CSA treatment already during initial therapy (supplemental Figure 1, available on the Blood Web site; see the Supplemental Materials link at the top of the online article). In total, 9 (36%) patients with major treatment changes survived. Presenting features. ...