HLA-DQ2 and DQ8/DR4 allele identification was performed using Real-time PCR technique. According to the obtained results a total of 26% (n=6) of tested patients were positive for HLA-DQ2 and HLA-DQ8/DR4 alleles. Two of the patients were positive for HLADQ2 alleles and four patients ...
现在可以搜索hla分型查看HLA-DQB了，HLA-DQ2也就是HLA-DQB*02：01和02：02是高风险，还有HLA-DQ8...
Presents a letter to the editor about the association of the human leukocyte antigen DQ2 and/or DQ8 with celiac disease-specific autoantibodies to tissue transglutaminase in families with thyroid autoimmunity.American Journal of Gastroenterology (Springer Nature)Badenhoop...
Celiac disease, HLA DQ2, HLA DQ8, epidemiologyStudies suggest that vitamin D may be involved in the pathogenesis of allergic disorders, asthma and decreased lung function. However, results are inconsistent and only few prospective studies have examined adults. The purpose of this study was to ...
HLA-B27 HLA-DQ2DQ8 HPV(附翻译)HLA-B27 Definition. HLA-B27 findet sich bei etwa 8 % der kaukasischen Bevölkerung auf der Oberfläche von Leukozyten und ist stark mit dem Vorkommen des Morbus Bechterew (ankylosierende Spondylitis), aber auch anderer Störungen mit einem Autoimmun...
HLA-DQ8trans is the HLA molecule that confers the highest risk for human type 1 diabetes (T1D), yet the reason for this risk remains elusive. Using tetramer-guided epitope mapping, we discovered a high degree of peptide overlap between DQ8 and DQ8trans for antigens from influenza A viruses...
4 which generally are much better recognized by the T cells after deamidation by the enzyme transglutaminase 2 (TG2).5,6 The strong HLA association of celiac disease with HLA-DQ2 and HLA-DQ87 and selective recognition of gluten peptides in the context of the very same HLA molecules by ...
ARTICLES nature publishing group Single-chain recombinant HLA-DQ2.5/peptide molecules block 2-gliadin-specific pathogenic CD4+ T-cell proliferation and attenuate production of inflammatory cytokines: a potential therapy for celiac disease J Huan1,2, R Meza-Romero1,2, JL Mooney1,2, AA Vandenbark1...
Results The HLA-DQ pattern of the 31 CD children was: hetero DQ2 ( n =15), DQ2 with homo β2 (10), DQ8 and β2 positive (3), DQ8 (2), and hetero β2 (1). The HLA-DQ pattern of the 156 controls was: hetero DQ2 ( n =36), hetero β2 (30), DQ2–DQ8 negative (23...
HLA-DQ2 and HLA-DQ8 Are Expressed on So-Called Antigen-Presenting CellsFrits Koning