HLA-matched red blood cells may not be necessary if you have the ability to create a selected donor pool, by identifying donors of red cell units that have not produced a previous reaction.WoodsOhioJ.J.OhioKosankeOhioJ.OhioWisselOhio
HLA antigens on red blood cells responsible for hemolytic transfusion reactions: KL Pierce, SA Hackbarth, ST Johnson, LA Weitekamp, DD Eckels, The Blood Center of SE Wisconsin, Milwaukee, WIdoi:10.1016/0198-8859(93)90413-UMuthu, S.
HLA antigens on peripheral red blood cells:analysis by flow cytofluorometry using monoclonal antibodies. de Villartay JP,Rouger P,Muller JY,Salmon C. Tissue Antigens . 1985Villartay JP, Rouger P, Muller JY, Salmon C: HLA antigens on peripheral red blood cells: analysis by flow cyto...
Cells from Fanconi anemia (FA) patients are hypersensitive to alkylating agents and radiation traditionally used as conditioning regimens for marrow cell transplantation, and patients experience serious toxicities. To reduce toxicities, we used progressively lower doses of cyclophosphamide (CY) for condition...
proposed to overcome the hurdle, including transplantation of HLA-matched allogeneic induced pluripotent stem cells (iPSC)-derived cells [1], transplantation of allogeneic cells with the administration of an immunosuppressant [2,3,4,5], and development of genetically engineered hypoimmunogenic cells [6...
Myeloid-derived suppressor cells (MDSCs) are proposed to control graft-versus-host disease (GVHD) in allogeneic hematopoietic stem cell transplantation (allo-HSCT). However, the definition of human MDSCs has not yet reached consensus, and the mechanism o
Human leukocyte antigens (HLA) are specialized proteins present on the surface of all cells in the body except red blood cells. The HLA genes that individuals inherit are responsible for the HLA antigens present on their cells. HLA testing identifies the major HLA antigens that are present on...
CCR5 expression on cells from HLA-matched unrelated marrow donors and graft-versus-host disease. Graft-versus-host disease (GVHD) is a common complication that is caused by donor T cells following allogeneic hematopoietic cell transplant. Recently, the... Q Ma,TA Gooley,RF Storb - 《Biology ...
We constructed a pool of random peptides (8–15 amino acids long) and sampled a large number of length-matched decoy peptides with the observed allele to avoid bias. We excluded all peptides, including both hits and decoys, that contained non-canonical amino acids. Decoy generation for ...
Normal human peripheral blood cells were either left unstained (blue histogram) or stained with HLA-A2 Monoclonal Antibody, NovaFluor Red 710 (purple histogram). Total viable cells in the lymphocyte gate were used for analysis, as determined by LIVE/DEAD Blue (Product # L34962). Data was acq...