To do this, TPM values of the CD8A and CD8B genes were first converted to log2, and the mean log2 value across the two genes was taken for each sample. Calling alternative splicing in all protein-coding genes To call alternative splicing in all protein-coding genes, we used the STAR ...
surface expression7,8,9. VL9 peptide-bound HLA-E complexes engage the natural killer (NK) cell inhibitory receptor, CD94-NKG2A, thereby protecting healthy cells from NK cell-mediated lysis6,9. HLA-E also binds the NK cell activating receptor, CD94-NKG2C, although such interactions are of ...
人T细胞表面有能与绵羊红细胞结合的受体,称为E受体,E受体在体外可与绵羊红细胞表面的配体在一定条件下结合,可在T细胞表面形成花环状,称为E花环。用这个方法可以检测人外周血T细胞的相对百分数,可作为判断人T细胞免疫功能指标之一。 E受体已证明是分子量...
Thermo-life MA110302 ANTI-CD8A EA ￥3,613.00 EA Thermo-life MA110305 ANTI-CD8A EA ￥3,613.00 EA Thermo-life MA110307 ANTI-CD9 EA ￥3,613.00 EA Thermo-life MA110312 ANTI-CD9 EA ￥3,613.00 EA Thermo-life MA110313 ANTI-CD95 / FAS EA ￥3,613.00 EA Thermo-life MA110314 ANTI-CD98 ...
HLA-C expression on CD3eCD8alymphocytes was significantly higher for the CC or CT genotype than for the TT genotype of rs9264942. The TACC haplotype of the four SNPs was associated with a strong susceptibility to ulcerative colitis (UC) but protection against Crohn's disease (CD) as well ...
用 FITC标记抗人CD8a~[IPE标记抗人IFN—Y的流式单抗 枸橼酸 (0.131mol/L枸橼酸和0.061mol/L磷酸氢 购自美国Biolegend公司,ELISPOT分析仪来 自北京 二钠,pH3.2)处理细胞90s以洗脱表面HLA—A1101、 赛智创业科技有限公司,FACSCalibur流式细胞仪 A2402分子肽结合凹槽中结合的肽_1引。细胞经PBS 来自美国BD...
22-0408-45 Cocktail of FITC anti-human CD4 (RPA-T4) and PE anti-human CD8a (RPA-T8) 50 tests 16-5983-82 Functional Grade Purified anti-human B7-H1 (CD274, B7H1, PD-L1, PDL-1, PDL1) 100 ug 12-0559-73 PE anti-human CD55 100 tests 12-1038-73 PE anti-human CD103 (Integrin...
[0241]k)将CD8a结合HLA-G抑制超过80%(当与没有抗体的情况中的结合比较时)(见实 施例4c);和/或 [0242]l)恢复与JEG-3细胞(ATCC HTB36)共培养的单核细胞的HLA-G特异性受遏制免疫 应答(例如受遏制肿瘤坏死因子(TNF)α释放)。 [0243]本发明的一个实施方案是一种(分离的)结合人HLA-G的抗体(在一个实施方...
For HLA detection on immune cells, the following antibodies were used: Mouse anti-human V450 CD4 (BD, 560345), APC-Cy7 CD8a (Tonbo, 25–0088-T100), BV421 CD56 (BioLegend, 318328), FITC CD19 (eBioscience, 11–0199-42), BV510 HLA-ABC (BioLegend, 311436), PE-Cy7 HLA-DR (e...
NK 细胞上 的 HLA—E 受体) 对于淋 巴细胞 的识别更为重要 ,目前仍存在疑问。 5 I-ILA-G 的功能 5.1 HLA—G 与 T 淋巴细胞之间的作用 Sande~ 等 首先通过展示表达 HLA—G 的细胞可与 CD8a 细胞 结合,从而证明 HLA—G 对 T 淋 巴细胞有影 响。Shi— ...