There are very few cohorts with longitudinal measurements of HIV VL and CD4+ T cell counts (CD4 counts) among ART-naive individuals since the successful implementation of a universal test-and-treat (UTT) strategy, where ART is started following HIV diagnosis regardless of CD4 count and WHO ...
At 3 months after HSCT, the peripheral blood counts of CD4+ T cells were 129.00 (24.88-510.82·μL−1. The median of CD8+ cell counts at +60 days was 526.50 (4.54-2742.73)·μL−1 and returned to normal (median: 656.3·μL−1; range: 50.92·μL−1-3708.04·μL−1) ...
K Nishimaki T Kawamura H Inada K Yagawa Y Nose N Nabeya G Isshiki N Tatsumi S Niihira (2000)HLA DPB1*0201 gene confers disease susceptibility in Japanese with childhood onset T1D, independent of HLA-DR and DQ genotypesDiabetes Res Clin Pract471 49–551:CAS:528:DyaK1MXnslyhu7w%3D1066022...
Moreover, we found that S100A9+ monocytes exhibited profound immunosuppressive function on CD4+ T cell immune response and blockade of S100A9 using Paquinimod could partially reverse sepsis-induced immunosuppression. Conclusions This study identifies HLA-DRlowS100Ahigh monocytes correlated with ...
were analyzed. The cell numbers and percentage of all MDSCs were significantly increased in G-PB and G-PBSC. M-MDSC population increased in both frequency and absolute number in G-PBSC. HLA-DR−/lowCD33+CD16−population increased in both frequency and absolute number in G-PB and G-PBSC...
Viral infection is more frequently reported in cord blood transplantation (CBT) than in transplantation of other stem cell sources, but its precise mechanism related to antiviral host defenses has not been elucidated yet. To evaluate the effect of human
The human leukocyte antigen (HLA) haplotype DRB1*15:01 is the major risk factor for multiple sclerosis (MS). Here, we find that DRB1*15:01 is hypomethylated and predominantly expressed in monocytes among carriers of DRB1*15:01. A differentially methylate
Differential methylation atMHCin CD4+T cells is associated with multiple sclerosis independently ofHLA-DRB1 ArticleOpen access18 July 2017 Introduction Multiple sclerosis (MS), a leading cause of neurological disability in young adults, is a chronic inflammatory disease of the central nervous system (...
S Easteal M Viswanathan SW Serjeantson (1990)HLA-DP,-DQ and -DR RFLP types in south Indian insulin dependent diabetes mellitus patientsTissue Antigens352 71–741:STN:280:By%2BB28%2Fos1Q%3D1971463 CASPubMedGoogle Scholar K Nishimaki T Kawamura H Inada K Yagawa Y Nose N Nabeya G Isshiki...
CD8+T cells in this process5,6,7. Expression of certain class I human leukocyte antigen (HLA) alleles, particularly at the HLA-B locus8,9, is associated with lower plasma viral loads, higher CD4+T cell counts and delayed onset of AIDS10,11. Interaction between CD8+T cells and viral ...