MHC基因B52阳性可能与强直性脊柱炎相关。人类白细胞抗原（HLA，人MHC）是人类基因组中最复杂、最具遗传多态性的基因系统，是研究人类学和遗传学的重要遗传标记；是人类免疫系统中重要的组成部分，参与了机体细胞免疫和体液免疫等重要过程，与许多疾病密切相关；HLA还是机体识别自我和非我的标志，是人的移植...
HLA-B51 is one of two distinct split-antigens of the HLA-B5 serotype and is primarily associated with BD risk, although some case reports have also found a possible link with the second split-antigen, HLA-B52 [89, 90]. Several HLA-B51 subtypes have been described, of which especially ...
会诊意见:建议查HLA-B27、ESR及CRP、免疫球蛋白,以明确是否存在免疫相关性疾病至葡萄膜炎。 经检查,该患者人类白细胞抗原B27核酸检测阳性。证实了该病人为HLA-B27抗原相关的急性前葡萄膜炎。 治疗方案及疗效:妥布霉素地塞米松滴眼液、双氯芬酸钠...
Hishizawa等[4]发现一名67岁男性再障患者在一次输血小板2小时后发生输血相关性急性肺损伤(TRALI)。后发现在该血液制品供者血清中存在抗HLA抗体(HLA B52抗体),淋巴细胞毒性试验显示该抗体介导针对患者细胞的细胞毒性。因此建议在血液制品输注前应对其供者进行抗HLA抗体的检测,...
Behet disease with neurological involvement associated to HLA-B35 and HLA-B52Valdez, YaninaGomez, CatalinaLedesma, RaulPolish Archives of Internal Medicine
HLA-B-B5(B51 - B52) - B7 - B8 - B12 (B44 - B45) - B13 - B14 (B64 - B65) - B15 (B62 - B63 - B70 - B71- B75 - B76 - B77) - B16 (B38 - B39) - B17 (B57 - B58) - B18 - B21 (B49 - B50) - B22 (B54 - B55 - B56) - B27 - B35 - B37 -B40(B60-B...
抗原宽特异性 分解物 B5 B51，B52 B7 B703，B705 B12 B44，B45 B14 B64，B65 B15 B62，B63，B75，B76，B77，B1508，1511 B16 B38，B39，B3901，B3902，B67 B17 B57，B58 B21 B49，B50，B4005 B22 B54，B55，B56 B40 B60，B61 B70 B71，B72 DR位点 抗...
24、抗体,选择抗原匹配的单采供者;交叉反应组相容抗原特异性A01CA1、A3、A11、A29、A30、A31、A36、A80A10CA10、A11、A19、A25、A26、A32、A33、A34、A43、A66、A74A02CA2、A9、A23、A24、A28、A68、A69、A203、A210、A2403、B17、B57、B58B05CB5、B18、B35、B51、B52、B53、B78、B5102、B5103B07CB...
•对于原发病高危组:案可以选用1~2个位点不和的供者. 杂合体易接受错配,而纯合体不易接受错配. P HLA –A2, - HLA-B33, 41 HLA-DR11,10 D1 HLA-A2,- HLA-B52,41 HLA-DR11, 10 D2 HLA-A2,A3 HLA-B33 ,41 HLA-DR11,10 次要组织相容性抗原(MiHA)©...
with broad specificities, new serotypes appear that identified a smaller set of antigens more precisely. These broad antigen groups, like A9 and B5, were subdivided into "split" antigen groups, A23 & A24 and B51 & B52, respectively. As the HL-A serotyping so did the identification of new...