以下内容仅对HLA-B27基因检测试剂说明书的重点内容进行详细说明,说明书其他内容应根据《体外诊断试剂说明书编写指导原则》要求进行编写。 1.【预期用途】 应至少包括以下几部分内容: 1.1本产品用于体外定性检测人体静脉外周血样本中的HLA-B27基因。 1.2介绍被测基因与临床适用症的关系,明确HLA-B27在中国人群中的分布频...
HLA-B27 in 1982: Reappraisal of a Clinical Test 来自 NCBI 喜欢 0 阅读量: 27 作者: A Calin 摘要: Editorial. Focuses on several issues regarding medicine. Discussion on probability reasoning in clinical decision making; Introduction of Bayesian analysis; Information on several case histories of ...
MHC class I molecule; MHC class I protein; MHC class II antigen; MHC class l antigen; MHC classI antigen; MHC HLA-B cell surface glycoprotein; MHC HLA-B transmembrane glycoprotein; MHC HLA-B27-HS; MHC HLA-B27d; MHC HLA-B39N; truncated class I antigen; truncated MHC class I antigen ...
Khan MA. Clinical application of the HLA-B27 test in rheumatic diseases. A current perspective. Archives of Internal Medicine 1980;140(8):1097-8.Khan MA. Clinical application of the HLA-B27 test in rheumatic diseases. A current perspective. Archives of Internal Medicine 1980;140(2):177-80....
产品摘要:HumanleucocyteantigenB27,HLA-B27ELISAKit上海杰普斯生物科技有限公司是一家注于免疫检测类试剂的高科技生物公司,主要产品为ELISA试剂盒、生化试剂盒、培养基、血清、外包服务和其它相关配套试剂。 支付方式: 支付宝微信银行转账 产品完善度:访问次数:420 ...
instead to test whether the mouse accessory molecule Lyt-2 on cytotoxic T lymphocytes could interact efficiently with the α3 domain of HLA. To do this, we replaced the α3 domain of HLA-B27 by a murine α3 domain in a gene construct used to produce transgenic mice, and then used the ...
HLA-B27 belongs to the MHC class I molecules. Its main function is the presentation of intracellular peptides to CD8-positive T lymphocytes. These MHC class I-restricted T cells possess cytotoxic or regulatory function, their activation leading accordingly either to tolerance, when the presented ...
Hence, for each CMV- associated TCRβ and each HLA-A and HLA-B allele identified for the subjects in cohort 1, we performed a Fisher's exact test13 to assess the significance of the enrichment of that TCRβ among subjects positive for that HLA allele. At a significance threshold of P ...
Similarly, B*4012 and B*4440 were found to have B27 supertype B pockets, associated with a preference for positively charged residues, when a B44 supertype specificity for acidic residues might have been expected. Table 8 Unexpected and/or revised supertype assignments. Full size table As noted...
7 Late escape may be a consequence of the number and complexity of the mutations required to generate a replication-competent T-cell escape variant, as in the case of the immunodominant HLA-B27–restricted epitope in Gag, KK10, for which a combination of 3 amino acid substitutions are ...