HLA-B27阳性组远高于HLA-B27阴性组,分别占23.4%和9.4%,且两组间差异明显,这与既往文献报道一致;而外周关节炎的发生率两组间并无明显差异,分别为31.3%(20例/64例)和25%(8例/32例)。
Patients with HLA-B27 positive AAU share ahigh risk for other genetically associated diseases, especially spondylarthritis, chronic inflammatory bowel diseases and psoriasis. As up to 40% of those affected have asystemic disease that has not yet been diagnosed, the ophthalmologist is of major ...
有推测认为HLA-B27相关性疾病可能是因一种特殊的多肽或多肽家族与HLA-B27结合而导致发病[10]。 四、环境因素与脊柱关节病(SpAs) 尽管大量的临床证据、流行病学及实验资料均证实SpAs发病与HLA-B27相关,但SpAs发病并非与HLA-B27绝对相关,并不是100%的SpAs患者均为HLA-B27阳性,调查显示HLA-B27阳性者也仅有1~6.7%...
Systemic diseases should be noted in HLA-B27 positive patients. KEY WORDS HLA-B27; acute anterior uveitis ;clinical features Corresponding author: He Yu Tel Email: qinghao.100@163.com FuLing Center Hospital of ChongQing City ,ChongQing,408000,China 葡萄膜炎是一类由多种原因引起的葡萄膜炎症,任何...
研究发现,人类白细胞抗原-B27(简称HLA-B27)在AS的发病中有着极为密切关系,90% 以上AS患者HLA-B27基因检测为阳性,而正常人群的 HLA-B27 阳性率约为5% ,这类人群罹患AS的几率约为6%。因此,HLA-B27在强直性脊柱炎的早期诊断中发挥着重要的作用。 HLA-B27的结构与功能 ...
@年斗肠道革兰阴性菌HLA-B27及反应性关节炎 中国^民解放军总医院风湿科!耋—R'弓zf 风温热是最先被证实由链球菌癔染所引起的一种 风湿性疾病.其后,感染在风湿病中越来越显出其重 要性.近20余年国外发现感染和遗传因子与反应性 关节炎(ReA)的关系尤为密切,现综述如下. 一 ,ReA的历史背景及定义1916年Relter...
聚合酶链式反应SSP 法和酶联免疫吸附试验检测强直性脊柱炎患者HLA-B27的比较[J]. 工企医刊,2014,27(3):800-801. PENG Ping, ZHANG Hao, XIE Lihua. Comparison of polymerase chain reaction SSP method and enzymelinked immunosorbent assay for detecting HLA-B27 in patients with ankylosing spondylitis [J...
流式细胞术检测HLA-B27抗原的表达及临床意义 患者中9例结果为阳性,阳性率为0.78%,71岁以上患者中7例结果为阳性,阳性率为0.61%.结论 青年男性HLA-B27阳性比例较高,HLA-B27检测对于关节疾病诊断具有重要意义... 廖德权,成捷,许蓝月 - 《临床检验杂志(电子版)》 被引量: 0发表: 2020年 A...
HLA-B27A 35-year-old man, with positive HBV and HCV markers, showed clinical and histopathological features of polyarteritis nodosa (PAN), in the course of HLA-B27 positive ankylosing spondylitis (AS). The possible occurrence of both diseases in genetically susceptible subjects is discussed. ...
5、 in the anterior chamber,often accompanying with systemic arthritic diseases.ConclusionsThere was significant difference in clinical feature between the HLA-B27 positive and HLA-B27 negative acute anterior uveitis. Systemic diseases should be noted in HLA-B27 positive patients.KEY WORDS HLA-B27; acu...