国外Popov等[15]运用经照射过的HLA-B27转基因鼠的脾细胞去刺激已用HLA-B27+细胞免疫接种过的HLA-B27鼠的脾细胞时,则不能产生可破坏HLA-B27+靶细胞的细胞毒性T淋巴细胞(即产生了免疫耐受);但如果HLA-B27+细胞免疫接种过的HLA-B27鼠脾细胞预先...
则不能产生可破坏HLA-B27+靶细胞的细胞毒性T淋巴细胞(即产生了免疫耐受);但如果HLA-B27+细胞免疫接种过的HLA-B27鼠脾细胞预先与沙眼衣原体共同孵育(即免疫耐受被打破)后,则能产生可破坏HLA-B27+靶细胞的细胞毒性T淋巴细胞。
which involves the iris and the anterior part of the ciliary body. It is characterised by a cellular infiltration in the anterior chamber and often in the anterior vitreous. Keratic precipitates and endothelial dust are not uncommon in HLA-B27-associated disease. There may be some “spillover”...
A diagnosis of HLA-B27--associated uveitis may bring an associated systemic condition to medical attention for the first time. Ongoing research promises to elucidate the intriguing relationship between the HLA-B27 molecule, gram-negative bacterial infection, and inflammatory disease. 展开 关键词:...
HLA-B27 determination should be performed in all cases of acute anterior uveitis (AAU), since B27+ AAU is a distinct kind of uveitis. All B27+ AAU ... Feltkamp,T. E. W. - 《Current Eye Research》 被引量: 30发表: 1990年 Dysfunction of HLA-B27 Ivanyi P: Dysfunction of HLA-B27: A...
AB0667 Hlab27 Associated Uveitis Trends and Patterns of A Multiethnicity Cohort: Need for Combined Rheumatology and Eye Services?BackgroundUveitis is associated with systemic autoimmune disease and often present to Eye Department as an emergency. Uveitis can be a first presenting symptom of systemic ...
HLA-B27是阳性 抗着丝点抗体弱阳性 一定是强直性脊柱炎吗 时继昌 你好! ask_345441 你好 时继昌 这个情况考虑是此病的可能性大 ask_345441 多大 时继昌 骶髂关节的片子有没有拍? ask_345441 昨天做了CT 报告还没出来 时继昌 嗯 时继昌 半分之80吧 ask_345441 80?在 ask_345441 要80了 时...
HLA B27 is a class Imajor histocompatibility antigen, which predisposes to several diseases includingankylosing spondylitis, reactive arthritis (Reiter's syndrome),inflammatory bowel disease, andpsoriasis. It also predisposes touveitis, with or without one of the other conditions. HLA B27 uveitis compris...
Toll‐like receptors in ocular immunity and the immunopathogenesis of inflammatory eye disease In addition, microbial agents have been implicated in the pathogenesis of "non‐infectious" immune mediated diseases such as HLA‐B27 associated acute ... Chang,J H - 《British Journal of Ophthalmology》 ...
Both AAU and ankylosing spondylitis are strongly associated with HLA-B27. HLA-B27 affects the composition of the gut microbiome, which in turn can modify the immune system and thereby affect health and disease. The intestinal microbiome is strongly implicated in the pathogenesis of AAU and ankylosin...