首先,参与HLA-B*1502药物安全基因检测的患者需要提供开具有效期内的《健康证》。患者需要接受检测前提供其居住地区及出生地社保编号等资料,以确保患者是当地居民。此外,患者还需提供出生日期、性别、身份证号码等资料,以防止身份信息失真。 其次,参与HLA-B*1502药物安全基因检测的患者需提供病例和医疗记录。病史以汇总...
HLA-B* 1502基因检测可以通过多种方式进行。常见的检测方法有基因测序、外显子映射和免疫小分子测序。基因测序是一种检测方法,其目的是通过精确识别基因碱基序列,检测患者在HLA-B* 1502位点是否具有潜在的药物过敏风险。外显子映射是指测量某个基因的外显子,以确定患者特定基因位点(表观遗传学位点)上等位点的存在,...
HLA-B*1502 是人类白细胞抗原(Human Leukocyte Antigen,HLA)的标记,主要用来预测在使用一些特定药物进行治疗之前,患者接受该特定药物有可能产生严重不良反应的风险。 临床药师建议,在给予患者某些与HLA-B*1502有关药物,如某些抗癫痫或肝病抗病毒药物时,应首先进行HLA-B*1502基因检测。其原因在于,患者有HLA-B*1502 ...
Sensitivity and specificity of this HLA-B*1502 genotype test were 94.1% and 82.5%, respectively, while the positive predictive value and negative predictive value were 1.43% and 99.98%, respectively. Positive and negative likelihood ratios were 5.37 and 0.07, respectively.Conclusions: HLA-B*1502 ...
如果测试是否存在 hla-b * 1502年基因应该建议执行高分辨率 hla-b1502 基因分型 翻译结果4复制译文编辑译文朗读译文返回顶部 如果测试的存在HLA-B*1502显性应要求进行了高HLA-B1502基因冰建议 翻译结果5复制译文编辑译文朗读译文返回顶部 如果测试对于hla-b *1502等位基因的出现应该要求perfomed被推荐的高分辨率hla-...
该引物是根据HLA-B*1502基因的第2和第3外显子区域设计的,用以定性检测待测样品中的HLA-B*1502基因. This primer is based on the second and third external HLA-B * 1502 gene exon region designed for qualitative detection of the test sample HLA-B * 1502 gene. 所述引物的上游引物具有序列表中SEQ...
Food and Drug Administration. The FDA said that carbamazepine should not be initiated in patients with HAL-B*1502 allele. It also warned that CSS and TEN can still develop in patients who test negative for this allele.EBSCO_AspCNS Disorders Today...
Main outcome measure Comparison of the costs of treatment of CBZ induced SJS/TEN and costs of HLA-B*1502 screening test. Results When persons having the HLA-B*1502 allele receive CBZ, the chance of developing SJS/TEN is as high as 88.1 %, while persons without the HLA-B*1502 allele do...
HLA-B*5801,HLA-B*1502基因检测试剂盒,可用于检测病毒感染,以及药物抗原表达及抗药性。HLA-B*5801基因检测百度百科表明,该基因可以用来检测HIV感染的抗原表达形式以及抗药性,可用于预防HIV和药物抗原表达形式,并减少不良反应的风险。 总之,HLA-B*5801药物安全基因检测是世界各国药物安全法组织规定的一项重要的技术,能...
Objective The HLA‐B*1502 allele is strongly associated with carbamazepine (CBZ)‐induced Stevens–Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) in the Han Chinese population. This study investigated the impact of HLA‐B*1502 screening on CBZ utilization and rates of severe cutaneous allergic...