· 3 1 1 1 · 稳定表达HLA-A * 1101 蛋白的 K562 细胞株的建立 Table. Primers used for construction of HLA-A * 1101-encoding expression vector Name Sequence Description A11F1 5'-CAGACGCCGAGGATGGCC-3' The sense primer of HLA-A * 1101 gene. A11R 5'-CACACAAGGCAGCTGTCTCACA-3' The re...
Disclosed are: HLA-A * 1101-restricted WT1 peptide, specifically a peptide consisting of WT1 protein containing nine contiguous amino acid residues of the amino acid sequence capable of binding to HLA-A * 1101 molecule, and having the ability to induce CTL ; peptide dimer comprising two peptide...
Do I need to know the sequence of the UV-labile peptide? The sequence of the UV-labile peptide is not needed to use the reagent. MHC molecules are not stable without a peptide, so these peptides are used just for two purposes: stabilize the MHC molecules and serve as a place ...
高效准确鉴别 HLA 基因分型 针对聚合酶链反应-序列特异性引物 (polymerase chain reaction-sequence specific primer, PCR-SSP) 的 HLA 基因分型检测方法,Medix Biochemica HiDi®系列原料酶对于引物3'末端仅单独一个错配,即具有高特异性,且无论是转换型或颠换型错配,均可高效鉴别,极大程度提高了HLA基因分型的效...
HLA 基因具有高度的多态性,决定了所表达的 HLA 抗原分子的多态性。目前主要利用基因分型检测技术进行 HLA 分型,相较于血清学和细胞学方法,具有更高的灵敏度和准确度,并且可以检测出更多分型。 HiDi® 高效准确鉴别 HLA 基因分型 针对聚合酶链反应-序列特异性引物 (polymerase chain reaction-sequence specific pr...
HLA基因与生殖免疫相关性的研究人类白细胞抗原(HLA)是人类主要组织相容性复合体的产物,本质是具有高度多态性的同种异体抗原,按分布和功能分为Ⅰ类和Ⅱ类抗原, HLA-Ⅰ类抗原由HLA-A、B、C位点编码,HLA-Ⅱ类抗原受控于HLA-D区(包含DP ,DM , DO,DQ和DR5个亚区),...
HLA typing by sequence-specific oligonucleotide probe hybridization for blood donors 人类白细胞抗原(Human leucocyte antigen,HLA)是由位于第6号染色体短臂远端基因编码的两类独立的对T细胞表面具有高亲和性的多肽抗原,分为HLAⅠ和HLA Ⅱ。HLA在免疫系统的调控、器官移植、许多疾病如自身免疫性疾病和癌症以及人类遗传...
众多的DNA分型技术相继被发明,目前有三种主要的技术应用于临床及科研:序列特异性引物(sequence-specific primer,SSP)方法、序列特异性寡核苷酸探针(sequence-specific oligonucleotide probe,SSOP)杂交和DNA序列测定(sequence-based typing,SBT)。SSP技术是一种简单、低成本的用于HLA低、中分辨...
There has been a difference of two amino acids observed between the F pockets of the peptide binding groove of B*27:06 and B*27:04, as well as a difference of one amino acid between B*27:09 and B*27:05. These minor changes of the amino acid sequences result in significantly ...
Homo sapiens A1101 mRNA for HLA-A11 antigen A11.1, complete cds On Sep 21, 1994 this sequence version replaced gi:441045. L Lin,K Tokunaga,Y Ishikawa,... 被引量: 0发表: 1993年 We have detected an antibody against HLA—A11.1 Two new splits of HLA—A11.1 and A11.2,were identi—fie...