HIV 感染妇女宫颈疾病中P16INK4a 蛋白的表达飞秋月冯琳张红芸徐琳赵耀将成芹乔友林Journal of Kunming Medical University / Kunming Yike Daxue Xuebao
Patients suffering from CAP, which were referred to inpatient treatment, were enrolled into thedoi:10.1016/S1098-3015(10)61914-6SM BruniniJ ValadaresLCC GuimarãesBL AlmeidaCM SouzaValue in Health
目的p16 INK4A基因在与AIDS相关的疾病中有表达缺陷 ,DNA甲基化可使基因转录下调.本研究观察人类免疫缺陷病毒Ⅰ型 (HIV 1)感染对T淋巴细胞的 p16 INK4A基因的表达影响及其途径.方法 建立感染有野生型和突变体HIV 1病毒的T淋巴细胞Hut 78细胞系 ,以RT PCR,定量PCR和Westernblotting检测细胞感染后不同时间的DNA...
[目的]了解HIV阳性感染者宫颈脱落细胞P16INK4a蛋白表达与HPV感染的相关性.[方法]采用通用引物PCR和反向点杂交技术建立的检测方法,对182例HIV阳性感染者和300例HIV阴性感染者检测23种HPV亚型,包括18种高危型和5种低危型.同时采用免疫组织化学技术(S-P染色法)检测宫颈脱落细胞中P16INK4a蛋白表达情况.[结果]HIV阳性...
Results VL only partially drives expression of cleaved caspase-3 (CC3). CC3 hi HIV sp CTL in EC were not only lower compared to V (2.3 vs. 13%, respectively) but also l ...doi:10.1186/1742-4690-6-S3-P254SL HeathJ JiyuA BansalS SabbajJJ ShackaPA Goepfert...
及P16INK4a蛋白阳性表达率(18.7%)较HIV阴性者(19.3%,4.3%)高(P均为0.000).HIV阳性患者中,HPV感染阳性者宫颈脱落细胞P16INK4a蛋白表达率为43.3%,HPV阴性者4.3%(P=0.000); HPV多型感染者宫颈脱落细胞P16INK4a蛋白表达率(60.9%)较HPV单型感染者高(34.1%)(P=0.042);高危型HPV感染者宫颈脱落细胞P16INK4a...
P16-37. HIV controllers with weak CD8+ T cell responses maintain a tight control of infection despite carrying infectious virusesCell ResponseInfectious VirusTight ControlViral ControlStrong CapacityBackground HIV controllers (HIC) are rare HIV-1 -infected individuals who durably maintain undetectable ...
p16INK4aELISA did not perform well as a screening test for CIN2+ detection among HIV-infected women due to low specificity. Our study contributes to the ongoing search for a more specific alternative to HPV testing for CIN2+ detection....
An evaluation of p16INK4a expression in cervical intraepithelial neoplasia specimens,including women with HIV-1. Nicol AF,Golub JE,e Silva JR,et al. Mem Inst Os-waldo Cruz . 2012Alcina F Nicol,Jonathan E Golub,José R Lapa e Silva,etc.An evaluation of p16~(INK4a) expression in cervical...
P16INK4a Expression in Benign HPV Associated Oral Lesions in Hiv-Infected Patients: Clinicopathologic CorrelationCircadian rhythmDelayed sleep phaseFree-runPolysomnographyTau多道睡眠描记术Study Objectives: This study sought to characterize sleep and the circadian rhythm of body core temperature of an ...