Introduction: The development of an effective vaccine to protect against HIV is a longstanding global health need complicated by challenges inherent to HIV biology and to the execution of vaccine efficacy testing in the context of evolving biomedical prevention interventions. This review descri...
While advances have been made in some areas, more often than not attempts at vaccine development against the human immunodeficiency virus only serve to hig
While advances have been made in some areas, more often than not attempts at vaccine development against the human immunodeficiency virus only serve to highlight gaps in our knowledge of host immunity. While numerous approaches have been explored, to control infection, an HIV vaccine will need to...
This presentation will review the challenges and opportunities for development of vaccine candidates capable of eliciting broadly neutralizing antibodies against HIV. Highlights ► Recent advances have created a renaissance in the search for a safe and effective HIV vaccine. ► Most successful vaccines...
the evaluation of any breakthrough HIV-1 infections occurring among vaccinees during the vaccine trial and in ongoing vaccine development efforts in Thailand... K,O,Phan,... - 《Aids Research & Human Retroviruses》 被引量: 57发表: 2000年 Genetic impact of vaccination on breakthrough HIV-1 se...
Human immunodeficiency virus (HIV) immunopathogenesis and vaccine development: A review Marc P.Girard, ...Marie-PauleKieny, inVaccine, 2011 Abstract The development of a safe, effective and globally affordableHIV vaccineoffers the best hope for the future control of the HIV-1 pandemic. Since 1987...
HIV vaccine development has been slow and difficult. Although a priority from the moment HIV was discovered to be the cause of AIDS in 1986, only three products have completed efficacy testing in a...
To review the status of HIV vaccine developmentSince the discovery of HIV-1 in the early 1980s considerable effort has been exerted to develop a prophylactic vaccine, with relatively meagre results. The absence of natural immunity has proven to be a major stumbling block in identifying a mechanis...
HIV-1 entry into cells: Targets for drug and vaccine development. In 5th Conference on Retroviruses and Opportunistic Infections, February 1–5, 1998, Chicago, IL, USA Reitter, J.N., Means, R.E. & Desrosiers, R.C. A role for carbohydrates in immune evasion in AIDS. In Onzième ...
The quest for an effective and safe HIV-1 vaccine has been and still is the aspiration of many scientists and clinicians worldwide. Until recently, the hop