分析功能丰富 HIV-GenomePro软件具有病毒分型、基因组装、变异检测和进化溯源分析等功能,可实现耐药位点的精准预测和注释,还可合并多样本组装序列进行HIV-trace分析,获得分子网络图。 HIV-1耐药测序组合产品全流程 实测数据 以从血浆和培养毒株中提取的RNA为样本进行文库制备,基于DNBSEQ-G99ARS平台进行测序与分析,并与Sa...
HIV-TRACE(传输簇引擎):HIV-1和其他迅速发展的病原体的大规模分子流行病学研究工具 在分子流行病学的现代应用中,通常使用遗传序列数据来识别迅速发展的病原体(最显着的是HIV-1)中的传播簇。传统的“皮鞋”流行病学通过追踪共享流行病学联系(例如,性接触)的伙伴链来推断传播群。在这里,我们介绍一种用于识别此...
(31,285 of whom had wild-type virus containing no DRAMs), we inferred a total of 4366 molecular transmission clusters using a genetic distance threshold of ≤0.015 substitutions/site in HIV-TRACE (HIV TRAnsmission Cluster Engine)31, comprising 17,688 persons (42.7%). Of the 33,285 ...
使用HIV-Trace进行序列比对,而HIV-1亚型/亚亚型则通过使用最大似然方法的IQ-Tree v 2.0.6(7)构建系统发育树来确定。个体根据以下标准被纳入研究:年龄在18岁及以上,有采样年份和省级行政区域(PLAD)信息,可以获得蛋白酶和至少HXB2位置2,280-3,263的反转录酶初始238个氨基酸的信息,如果一个人有多个序列,选择最早...
his doctors said. Almost three years after receiving bone marrow stem cells from a donor with a rare genetic mutation that resists HIV infection - and more than 18 months after coming off antiretroviral drugs Ñ highly sensitive tests still show no trace of the man's previous HIV infection....
Methodological synthesis of Bayesian phylodynamics, HIV-TRACE, and GEE: HIV-1 transmission epidemiology in a racially/ethnically diverse Southern U.S. contextHOUSTON (Tex.)HIV infection transmissionDIAGNOSIS of HIV infectionsVIRAL transmissionRACIAL minoritiesMINORITIES...
hivtrace -i ./INPUT.FASTA -a resolve -r HXB2_prrt -t .015 -m 500 -g .05 -c Options Summary -i --input A FASTA file, withnucleotidesequences to be analyzed. Each sequence will be aligned to the chosen reference sequence prior to network inference. Sequence names may include munged ...
git clone https://github.com/veg/hivtrace-viz.git cd hivtrace-viz yarn yarn develop Navigate your browser to localhost:8273 Deployment The HIV-Trace webpage was formerly hosted using github-pages athttps://veg.github.io/hivtrace-viz/but has been migrated to using a pm2 process at hivtrace...
使用HIV-Trace进行序列比对,而HIV-1亚型/亚亚型则通过使用最大似然方法的IQ-Tree v 2.0.6(7)构建系统发育树来确定。个体根据以下标准被纳入研究:年龄在18岁及以上,有采样年份和省级行政区域(PLAD)信息,可以获得蛋白酶和至少HXB2位置2,280-3,263的反转录酶初始238个氨基酸的信息,如果一个人有多个序列,选择最早...
在公共卫生领域，基于ATOPlex多重PCR建库平台，华大智造已推出针对新冠、甲流乙流、猴痘、登革热等多种传染性疾病的即用型全流程测序组合产品。近期，华大智造新推出了针对HIV病毒和结核分枝杆菌的两款靶向扩增测序组合产品，全面涵盖HIV病毒和结核分枝杆菌及其耐药基因检测的建库-测序-分析全流程。ATOPlex技术特点HIV-1...