Mechanisms underlying activity of antiretroviral drugs in HIV-1-infected macro- phages: new therapeutic strategies. J. Leukoc. Biol. 80 (5), 1103-1110.Aquaro, S., Svicher, V., Schols, D., Pollicita, M., Antinori, A., Balzarini, J., Perno, C. F. (2006) Mechanisms underlying ...
Mechanism of HIV antiretroviral drugs progress toward drug resistancedoi:10.1111/j.1472-8206.2011.01009.xantiretroviraldrug resistanceHIVThe rapid replication rate of HIV-1 RNA and its inherent genetic variation have led to the production of many HIV-1 variants with decreased drug susceptibility. The ...
Due to the difficulty of achieving viral eradication, combination antiretroviral therapy is nowadays a realistic modality for the prolonged reduction of the viral burden. Antiretroviral drugs acting on different viral targets and/or on the same target but with different mechanisms of action have proved...
5. HIV Drug Resistance Twenty-four antiretroviral drugs belonging to six mechanistic classes have been licensed for HIV-1 treatment: Seven nucleoside and one nucleotide RT inhibitors (NRTIs), nine protease inhibitors (PIs), four non-nucleoside RT inhibitors (NNRTIs), one fusion inhibitor, one IN...
Antiretroviral medicines slow the progression of HIV. They are given in different combinations called highly active antiretroviral therapy (HAART). Your healthcare provider will decide what kind of HAART you need. You may need to make HAART changes if you have severe side effects or develop ...
Intracellular Pharmacokinetics of Antiretroviral Drugs in HIV-Infected Patients, and their Correlation with Drug Action In patients infected by HIV, the efficacy of highly active antiretroviral (ARV) therapy through the blockade of different steps of the retrovirus life cycl... Caroline,Bazzoli,Vincent,...
Objective Based on a critical evaluation of new data, to provide clinicians with recommendations on use of antiretroviral drugs for the treatment and prevention of HIV, laboratory monitoring, care of people aging with HIV, substance use disorder and HIV, and new challenges in people with HIV, inc...
Antiretroviral medicines slow the progression of HIV. They are given in different combinations called highly active antiretroviral therapy (HAART). Your healthcare provider will decide what kind of HAART you need. You may need to make HAART changes if you have severe side effects or develop ...
NANJING, June 7 (Xinhua) -- China Food and Drug Administration (FDA) has approved the sale of a new drug for the treatment of HIV-1 infection, the maker of the drug said. Aikening, or albuvirtide for injection (ABT), can be used with other antiretroviral drugs to treat infected patie...
ImportanceAntiretroviral therapy (ART) is the cornerstone of prevention and management of HIV infection.ObjectiveTo evaluate new data and treatments and incorporate this information into updated recommendations for initiating therapy, monitoring individuals starting therapy, changing regimens, and preventing HIV...