其他的意思也有类似于引导出的意思
在药物研发过程中，先导化合物扮演着重要角色。它是指通过生物测定，从众多候选化合物中筛选出的具有某种药物活性的新化合物。这种化合物通常具有新颖的化学结构，能够为后续的药物设计和开发提供基础。先导化合物的发现和选择，是药物研发过程中的关键步骤。通过筛选，科研人员可以从大量的化合物中挑选出最有...
and hit fragmentation, or any combination of ,想知道这段话中Hit to lead 是什么意思？
structure-activity relationship (SAR) studies to enter thelead optimization and preclinical developmentstage. With a dedicated team of skilled scientists and technicians,Creative Biostructureprovides MagHelix™ hit evaluation and lead identification (hit to lead) solutions to meet our clients’ needs ...
Hit to Lead also known as lead generation is a prerequisite for the construction of new drugs’ molecular structures and the key first step in the development of new drugs. This stage aims to obtain each hit series and try to produce more potent and selective compounds which possess pharmacokin...
Hit to Lead (H2L), automated chemical synthesis and lead optimization workflows for faster screening cycles and to reduce the overall drug discovery timeline.
The hit-to-lead process is composed of the general stages of hit assessment, hit validation, and identification of the best hits. The goal of any hit-to-lead effort is the identification of an optimal lead series and its liabilities for transition to lead optimization efforts. Although the ...
August 2006 REVIEWSHit discovery and hit-to-lead approachesGyo¨rgy M. Keseru˝1and Gergely M. Makara 21 CADD&HTS Unit, Gedeon Richter Ltd, 19-21 Gyo¨mro˝i u´t, Budapest, H-1103, Hungary2 Merck Research Laboratories, Merck & Co, RY80Y-325, 126 E. Lincoln Ave, Rahway, ...
New genetic mechanism could lead to RNA therapies for mental health Advancing obesity drug discovery: Cell-based assays for GLP-1 and the G-Suite The rise of organoids: a new era in drug discovery How GPCR agonists, including antibodies, are shaping the future of metabolic care FDA’s Projec...