In 1994, the total synthesis of taxol was a significant step towards producing anticancer drugs, and a gene called obese was cloned. There were also reports of quantum teleportation in 1997 and gravitational lensing— a key test of relativity theory — in 1993, as well as the synthesis of ...
The DNA story (A documentary history of gene cloning)doi:10.1016/0378-1119(82)90078-6E.H. SzybalskiElsevier B.V.GeneThe DNA Story: A Documentary History of Gene Cloning. . 1982
Cancer develops through a process of somatic evolution1,2. Sequencing data from a single biopsy represent a snapshot of this process that can reveal the timing of specific genomic aberrations and the changing influence of mutational processes3. Here, by
Such metaphors convey several messages: a definition of the gene as the basis of human destiny, an expectation that genetic research will enable the prediction of future disease, and a promise of therapeutic solutions. These messages are disseminated by a receptive press. ...
We present a phylogeny describing the evolutionary history of the UCP gene family and show that the genes have evolved through duplications followed by purifying selection except for a single site in the mitochondrial matrix between the 5th and 6thα-helices which has undergone positive selection.Back...
Red hair is a recessive genetic trait caused by a series of mutations in the melanocortin 1 receptor (MC1R), a gene located on chromosome 16. As a recessive trait it must be inherited from both parents to cause the hair to become red. Consequently there are far more people carrying the ...
its catalytic domain that suggest that these proteins may not have possessed poly(ADP-ribosyl)ation activity. Third, the diversity of the PARP superfamily is larger than previously documented, suggesting as more eukaryotic genomes become available, this gene family will grow in both number and type...
Glial cells are responsible for a wide range of functions in the nervous system of vertebrates. The myelinated nervous systems of extant elasmobranchs have... L Rotenstein,A Milanes,M Juarez,... - 《Gene Expression Patterns》 被引量: 8发表: 2009年 HISTOCHEMISTRY OF MYELIN. XIII DIGESTION ...
Mountain gorilla genomes reveal the impact of long-term population decline and inbreeding. Science 348, 242–245 (2015). Article CAS PubMed PubMed Central Google Scholar Scott, E. M. et al. Characterization of Greater Middle Eastern genetic variation for enhanced disease gene discovery. Nat. ...
5b,c). This SNP disrupted the exon–intron junction of the gene Tm.TA10622r1.3AG0164370, resulting in intron retention and the formation of an aberrant protein (Fig. 5d). A kompetitive allele-specific PCR (KASP) marker derived on this SNP co-segregated with the tin3 phenotype in a ‘...