With increasing rates of antibiotic-resistant bacteria and a dearth of new and novel antibacterial compounds in the pharmaceutical industry's research and development (R&D) portfolio, many public health officials, eminent scientists, and government leaders point to a growing crisis. In response, these...
A. Control of Gram-negative bacteria in experimental animals by streptomycin. Science 100, 103–105 (1944). Article CAS PubMed Google Scholar Schatz, A. & Waksman, S. A. Effect of streptomycin and other antibiotic substances upon Mycobacterium tuberculosis and related organisms. Exp. Biol. ...
The persistence of antibiotic resistance depends on the fitness effects of resistance elements in the absence of antibiotics. Recent work shows that the fitness effect of a given resistance mutation is influenced by other resistance mutations on the same genome. However, resistant bacteria acquire addit...
7. What can be inferred from the discussion of antibiotic-resistant strains of bacteria in paragraph 6? O Most microorganisms cannot survive multiple exposures to antibiotics. O tuberculosis strains are much more likely to be antibiotic-resistant than are other microorganisms. O Bacteria that rep...
Penicillin is one of the earliest discovered and most widely used antibiotic agents. While SirAlexander Flemingis credited with its discovery, it was French medical student Ernest Duchesne who first took note of the bacteria in 1896. Fleming's more famous observations would not be made until more...
The return of old diseases is the result of the fact that microorganisms are evolving species themselves. For example, new and serious antibiotic-resistant strains of tuberculosis have recently appeared. This evolution may have been encouraged by what some authorities consider our overuse of ...
Specifically, the development of antibiotics and the development of vaccines against pneumococci were important advances in modern infectious disease control. In addition, the emergence of antibiotic resistant bacteria marks an important development and highlights the need for new antibiotics, antibiotic ...
Identifying antibiotic-resistant strains via cell sorting and elastic-light-scatter phenotyping The proliferation and dissemination of antimicrobial-resistant bacteria is an increasingly global challenge and is attributed mainly to the excessive or im... S Narayana Iyengar,B Dowden,K Ragheb,... - 《App...
Understanding how bacteria survive periods of cell wall stress is of fundamental interest and can help generate ideas for improved antibacterial treatments. In this study we use tandem mass tagging to characterize the proteomic response of vancomycin resistant Streptomyces coelicolor to the exposure to su...
In other study, Krueger analyzed effect of streptomycin on protein synthesis in mammalian cells and found that this antibiotic altered the in vitro synthesis of antibody to phage MS‐2 in spleen and lymph node cells from immunized rabbits [85]. For protection or for cleaning up the cell ...