The precise trigger for the onset of puberty is not known, but it is believed to be a complex interaction between genetics, hormones, and environmental influences. Endocrine disruptors are environmental factors that have been implicated in causing early pubertal maturation. Industrial chemica...
The pool of primordial follicles present in the female ovary reaches its maximum number around 20 weeks of gestational age and then decreases in a logarith... NS Macklon,BCJM Fauser - 《Hormone Research》 被引量: 1375发表: 2000年 Neurobiological mechanisms of the onset of puberty in primates...
Unger F, Schröttner O, Haselsberger K, Korner E, Ploier R, Pendl G (2000) Gamma knife radiosurgery for hypothalamic hamartomas in patients with medically intractable epilepsy and precocious puberty. Report of two cases. J Neurosurg 92:726–731 CAS PubMed Google Scholar van Eyk HH (1897...
First children are, however, not typically born until some years after the onset of puberty. Other factors therefore contribute towards this delay. In this context, women's hips do not reach full adult form until they are in their mid-20s. Therefore, physiological and morphological factors ...
Friedreich's ataxia, a spinocerebellar degeneration, is an autosomal recessive disease of the cerebellum, spinal cord and peripheral nerves. Symptoms generally begin before puberty and include an ataxic gait, dysarthria, loss of reflexes and variably nystagmus, kyphoscoliosis and pes cavus. Heart ...
Friedreich's ataxia, a spinocerebellar degeneration, is an autosomal recessive disease of the cerebellum, spinal cord and peripheral nerves. Symptoms generally begin before puberty and include an ataxic gait, dysarthria, loss of reflexes and variably nystagmus, kyphoscoliosis and pes cavus. Heart ...
The authors think to have found two forms depending on the age of onset: one which breaks out with the beginning of puberty and the other group, which has a later onset, mostly related to a maturity step, such as the end of studies or the beginning of work life. Finally, the authors...