Histones play a critical role in packaging DNA in the eukaryotic nucleus and are heavily regulated by post-translational histone modifications. The core histones (H2A, H2B, H3, H4) assemble as dimers into structures called nucleosomes that hav...
Histone-Lysine N-MethyltransferaseProtamine KinaseHistonesProtein Processing, Post-TranslationalHistone CodeAcetylationMethylationCurr Biol. 2004 Jul 27;14(14):R546-51. Reviewdoi:10.1016/j.cub.2004.07.007Craig L PetersonMarc-André LanielElsevier Inc.Current Biology...
Microreview Histones and histone modifications in protozoan parasites Retina conditions and disorders, such as age-related macular degeneration (AMD), diabetic retinopathy (DR), retinitis pigmentosa (RP) and retinal or choroi... WJS Jr,A Naguleswaran,SO Angel 被引量: 0发表: 2006年 Histones and...
This new histone-replacement system provides a well-defined and direct cellular assay system for histone function with which to critically test models in chromatin biology dealing with chromatin assembly, variant histone functions and the biological significance of distinct histone modifications in a ...
Acetylated histone is not observed in new micronuclei during stages corresponding to anlagen development and, therefore, histone acetylation can be distributed ... M Fritzler - 《Journal of Clinical Investigation》 被引量: 433发表: 1978年 Cross-talk between Histone Modifications in Response to Histone...
Histone Modifications Lesson Summary Frequently Asked Questions What is a histone made of? Histones belong to a family of basic or alkaline proteins that are made up of positively charged amino acids. Histone proteins contain a large number of such amino acids as lysine and arginine. What are ...
美 英[hɪz'təʊnz] n.【生化】组蛋白 网络组织蛋白;组蛋白类;组蛋白抗体 复数:histones 英汉 英英 网络释义 n. 1. 【生化】组蛋白
Histone modifications This chapter presents four histone modifications and their functions in chromatin structure and function. The four core histones鈥擧2A, H2B, H3, H4鈥攁nd t... E Seto - 《New Comprehensive Biochemistry》 被引量: 50发表: 2003年 Chapter Six - Peptide Microarrays to Interrogate...
Histone Modifications Histones often undergo various modifications. Researchers have identified a significant number of these modifications. At times, histones may have a phosphate molecule added to them. Other instances involve the addition of long tails to histones. These modifications could be collective...
Given the broad interest in acetylation and transcription, addressing these questions is crucial for delineating the intricate relationship between histone modifications and gene regulation. Here we use quantitative mass spectrometry and three distinct small-molecule inhibitors of transcription to quantify the...