Additionally, in support of a post-transcriptional function, the yeast SET1 H3K4 methyltransferase responsible for H3K4me3 modification is recruited to the +300 bp region of genes after transcription initiation in yeast [48]. Elevated H3K4me3 levels occurring on genes with increased transcript production...
S3D. Taken together, these data show that M33 recruits G9a and SUV39H1 to induce heterochromatin formation through their histone methyltransferase activities. However, although both G9a and SUV39H1 interact with M33 and the chromodomain mutant M33(I17F), only G9a is recruited to M33(I17F)-...