A histidinol-phosphate aminotransferase mutant, engineering bacteria and the use of the histidinol-phosphate aminotransferase mutant in the production of indole-3-pyruvic acid. A histidinol-phosphate aminotransferase gene is derived from a Streptomyces luteoverticillatus strain HY61, and the nucleotide ...
The structures provide a model of how these different substrates could be accommodated by histidinol-phosphate aminotransferase. Some of the structural features of the enzyme are more preserved between the T. maritima enzyme and a related threonine-phosphate decarboxylase from S. typhimurium than with ...
2001. Structures of Escherichia coli histidinol- phosphate aminotransferase and its complexes with histidinol-phosphate and N-(5袌-phosphopyridoxyl)-L-glutamate: double substrate recognition of the enzyme. Biochemistry 40:4633-4644.Haruyama, K., et al., " Structures of Escherichia coli Histidinol-...
(1998) Molecular cloning and expression of a cDNA sequence encoding histidinol phosphate aminotransferase from Nicotiana tabacum. Plant Mol Biol 37, 1013-1022Malki EL,Frankard V,Jacobs M. Molecular cloning and expression of a cDNA sequence encoding histidinol phosphate aminotransferase from Nicotiana ...
The structures provide a model of how these different substrates could be accommodated by histidinol-phosphate aminotransferase. Some of the structural features of the enzyme are more preserved between the T. maritima enzyme and a related threonine-phosphate decarboxylase from S. typhimurium than with ...
coli histidinol-phosphate aminotransferase are homologous proteins. Only 12 amino acid residues out of a total of about 400 proved to be invariant in all sequences compared; they are either involved in the binding of pyridoxal 5'-phosphate and the substrate, or appear to be essential for the ...
Characterization of histidinol phosphate aminotransferase from Escherichia coli. Biochim Biophys Acta. 2003; 1647:321-4. [PubMed: 12686152]Mizuguchi H, Hayashi H, Hirotsu I M K, et al. Charac- terization of histidinol phosphate aminotransferase from Escherichia coli [ J ]. Biochim Biophys Acta,...
(2001) Crystal structure of histidinol phosphate aminotransferase (HisC) from Escherichia coli, and its covalent complex with pyridoxal-5'-phosphate and l-histidinol phosphate. J Mol Biol 311, 761-776SIVARAMAN J, Li Y, LAROCQUE R, etal. Crystal structure of histidinol phosphate aminotransferase (...
Crystalline L-histidinol phosphate aminotransferase from Salmo- nella typhimurium: purification and subunit structure. J. Biol. Chem. 248:1906-1911.Hsu, L. C., Okamoto, M. & Snell, E. E. L-Histidinol phosphate aminotransferase from Salmonella typhimurium. Kinetic behavior and sequence at the ...
Pyridoxal phosphate-dependent histidinol phosphate aminotransferase-HspAT enzyme is critically required for histidine biosynthesis. HspAT is involved in metabolic synthesis of histidine, phenylalanine, tyrosine, tryptophan, and novobiocin. We showed thatM. tuberculosisRv2231c is a conserved enzyme with Hs...