is released as part of the body's immune response, causing a variety of changes in the body including enlargement of the blood vessels, tightening of the airways, and faster beating of the heart. The itchiness and sneezing typical of an allergic reaction are caused by the release of ...
The formation of histamine in mammals is, to our knowledge, a unique process. The reaction is catalyzed by histidine decarboxylase, an enzyme which may undergo changes in activity as part of the adaptation of animals to variations of internal or external environment. The inducible type of histidin...
After overnight adherence, lung macrophages spontaneously released beta-glucuronidase (beta-G) at a rate of approximately 7 nmol of hydrolyzed substrate/h/million cells. Histamine at low concentrations (10(-9) to 10(-8) M) resulted in a consistent potentiation of this release. The concentration...
Histamine release in the hypothalamus and other target regions is highest during wakefulness. The histaminergic neurons display maximal activity during the state of high vigilance, and cease their activity during non-rapid eye movement (NREM) and rapid eye movement (REM) sleep. The cerebrospinal ...
OBJECTIVE: Decreased physician visits for dyspepsia were predicted with the histamine-2 receptor antagonists (H2RA) release to over-the-counter (OTC) statu... MJ Shaw - 《American Journal of Gastroenterology》 被引量: 565发表: 2001年 Histamine2-receptor antagonists. Standard therapy for acid-peptic...
Usingpersonal care products with toxic chemicals can cause your skin to release histamine. I try to stay at a 3 or below on the EWG’s standards. (You canread more about that on their site here.) For example, while I was working on reducing my histamine levels, I ended up having to ...
Indeed, the inflammatory response caused by histamine release has long been thought to be mediated by the histamine H1 receptor and H1 receptor antagonists, often referred to as antihistamines, have been used for years to treat allergies18. Commonly used histamine H1 receptor antagonists, such as ...
As an auto-receptor, H3R modulates the histamine release by the negative feedback8. While, as a hetero-receptor, H3R regulates the release of various neurotransmitters such as dopamine, γ-aminobutyric acid (GABA), and acetylcholine9. It was suggested that H3R was associated with several ...
Histamine appears to be necessary for the maintenance of the circadian rhythmicity of the adrenocortical hormone release, locomotor activity and food intake, and the sleep鈥搘akefulness cycle. In addition, a role for histaminergic neurons in the light entrainment is implicated. In phase shift ...
Cells were fixed with PBS containing 1% paraformaldehyde overnight at 4 °C then washed and resuspended in PBS supplemented with 2% FCS before analysis on BD LSRFortessa™ (BD). The instrument was calibrated with BD Rainbow Calibration Particles (BD) before each acquisition to ensure consistent ...