More recent findings, however, demonstrate that functional segregation also occurs along transverse axis of the hippocampus, within the hippocampal subfields CA1, CA2, CA3, and the dentate gyrus (DG). Because the functional heterogeneity within CA1 has been addressed in several recent articles, here...
The pyramidal cells in CA3 send some axons back to the dentate gyrus hilus, butthey mostly project to regions CA2 and CA1via the Schaffer collaterals.There are also a significant number of recurrent connections that terminate in CA3. (我觉的人的内向安静和外向活泼性格应该被CA1和CA3决定,因为只...
The calculation of hippocampal subregions confirmed the estimates that the volume of CA1 (547.1 mm3) is about half of the entire hippocampal formation (Sub 289 mm3, CA2 41.6 mm3, CA3 55.6 mm3, CA4 110 mm3 and DG 110 mm3). Fig. 1: Single image analysis. a, Cell body...
The hippocampus comprises four regions—CA1, CA2, CA3, and the dentate gyrus (DG). When information enters the hippocampus, it flows from the DG into CA3 and then passes through CA1 to the subbasal region. Different regions of the hippocampus play different roles in the overall information ...
Hippocampi were manually divided into 4 sub-regions (CA4, dentate gyrus (DG), CA3 and CA2/CA1) and their areas were measured. CD68 quantification was performed using the HALO® area quantification module, which measures stain-positive areas. CD8 + Tcells were quantified manually and ...
Remarkable hTau aggrega- tion from neurites to soma was observed in hippocampal subregions, including DG, CA3, CA2, CA1 and subicu- lum (Fig. 1g, h). Also, we found mild hTau368 expression in the entorhinal-piriform cortex (EC and Pir) and amyg- dala (Fig. 1c and Additional...
Figure 1: Super-resolution reveals PSD95 nanostructure and synaptic diversity in brain tissue. (a) Coronal section of the hippocampus from a PSD95-eGFP mouse. CA1, CA3 and dentate gyrus (DG) regions are shown. Scale bar 250 μm. (b) Left panel, confocal image from the CA1SO shows ...
DG 9.10 × 10−4 to 5.45 × 10−3 PVALB CA2/3 9.89 × 10−3 to 3.90 × 10−2 STMN1, SOD1, SYT1 CA1 1.32 × 10−3 to 4.66 × 10−2 STMN1, YWHAE, HSP90AA1 Cell-to-cell signaling and interaction CA4 1.41 × 10−3 to 1.12 × 10−2 GFAP, SNCA DG 1.82 ...
It is important to note that to minimize the partial volume effect [13], we combined the volumes of certain subfields: CA1 and CA2/3 were merged as CA1-3, CA4, and GC-ML-DG were merged as CA4-DG, and parasubiculum, presubiculum, and subiculum were merged as subiculum. As a ...
Functional differentiation in the transverse plane of the hippocampus: An update on activity segregation within the DG and CA3 subfields demonstrate that functional segregation also occurs along transverse axis of the hippocampus, within the hippocampal subfields CA1, CA2, CA3, and the dentate... MAA...