近年来大量研究发现Hippo-Yap通路在各种组织和器官的发育,再生,疾病和稳态中起到重要的调控作用。 2022年11月29日,来自美国德州大学的王俊团队在Circulation发表了题为Hippo-Yap Signaling Maintains Sinoatrial Node Homeostasis的文章【1】,首次...
2022年11月29日,来自美国德州大学的王俊团队在Circulation发表了题为Hippo-Yap Signaling Maintains Sinoatrial Node Homeostasis的文章【1】,首次揭示了Hippo-Yap信号通路在维持成年窦房结 (Sinoatrial node) 稳态中发挥关键作用。 窦房结是心脏的起搏器结构,心脏传导系统的重要组成部分,功能至关重要,能够启动和维持正常...
Hippo-Yap signaling also functions at the level of cellular development in a variety of organs through its effects on cell cycle control, cell survival, cell polarity, and cell fate. Because of its important roles in normal development and homeostasis, abnormal regulation of this pathway has been...
2022年11月29日,来自美国德州大学的王俊团队在Circulation发表了题为Hippo-Yap Signaling Maintains Sinoatrial Node Homeostasis的文章【1】,首次揭示了Hippo-Yap信号通路在维持成年窦房结 (Sinoatrial node) 稳态中发挥关键作用。 窦房结是心脏的起搏器结构,心脏传导系统的重要组成部分,功能至关重要,能够启动和维持正常...
The discrepancy concerning the Hippo-YAP signaling regulatory effect on osteogenesis and polarization direction were analyzed as well as propose the potential mechanism, which may be caused by the maturation of osteogenesis-related cells and heterogeneity of macrophages. More attention should be given to...
有ChIP-seq测序或组学研究需要的老师可联系易基因:0755-28317900. 参考文献: Sun X, Ren Z, et al. Hippo-YAP signaling controls lineage differentiation of mouse embryonic stem cells through modulating the formation of super-enhancers. Nucleic Acids Res. 2020 Jul 27;48(13):7182-7196....
2022年1月19日,东南大学首席教授柴人杰团队在Cellular and Molecular LifeSciences上在线发表了题为Hippo/YAP signaling pathway protects against neomycin-induced hair cell damage in the mouse cochlea的研究论文(Original Article)。 在本研究...
He XY, Fan X, Qu L, Wang X, Jiang L, Sang LJ, Shi CY, Lin S, Yang JC, Yang ZZ, Lei K, Li JH, Ju HQ, Yan Q, Liu J, Wang F, Shao J, Xiong Y, Wang W, Lin A. LncRNA modulates Hippo-YAP signaling to reprogram iron metabolism. Nat Commun. 2023 Apr 20;14(1):2253....
The Hippo signaling pathway: a potential therapeutic target is reversed by a Chinese patent drug in rats with diabetic retinopathy[J]. BMC Complement Altern Med, 2017, 17(1): 187. DOI: 10.1186/s12906-017-1678-3. 26. Wu D, Kanda A, Liu Y, et al. Involvement of Müller glial auto...
2022年11月29日,来自美国德州大学的王俊团队在Circulation发表了题为Hippo-Yap Signaling Maintains Sinoatrial Node Homeostasis的文章,首次揭示了Hippo-Yap信号通路在维持成年窦房结 (Sinoatrial node) 稳态中发挥关键作用。窦房结是心脏的起搏器结构,心脏传导系统的重要组成部分,功能至关重要,能够启动和...