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5. In my opinion, the hippo should live in a protected area like a zoo or a wildlife sanctuary in the future, as it has been accustomed to human care and may not be able to survive on its own in the wild. 答案1. 河马的名字是 Douglas。 2. 小河马在没有母亲的情况下活了下来,因为...
For neural induction, human pluripotent stem cells were seeded on 6-well Synthemax -coated plates (Corning) at a density of 2 × 106 cells/well and grown overnight in E8 medium. The next day, neural induction was initiated by adding fresh neural induction medium I (NIM I) ...
The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation Genes Dev., 9 (1995), pp. 534-546 Google Scholar 20 T. Xu, W. Wang, S. Zhang, R.A. Stewart, W. Yu Identifying tumor suppress...
(Table1; Fig.5). On the one hand, some studies believe that YAP is an important regulatory factor to promote OA. In mice and human OA models, it was found that the expression of YAP was up-regulated, and the levels of YAP mRAN and protein were higher than those of normal cartilage ...
The Hippo pathway transcriptional co⁃activator,YAP,confers resistance to cisplatin in human oral squamous cell carcinoma[J]. Int J Oncol,2015, 46(6):2364⁃2370. DOI:10.3892/ijo.2015.2948. [43] Attisano L,Wrana JL. Signal integration in TGF ⁃ β,WNT,and Hippo pathways...
Angiomotin and angiomotin like proteins, their expression and correlation with angiogenesis and clinical outcome in human breast cancer BMC Cancer, 6 (1) (2006), pp. 1-10 Google Scholar [64] L.R. Bringman, Specificity protein 1 induces the expression of angiomotin in response to IL-6/STAT3...
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human cancers, including NSCLC [158]. Rearrangement of the ROS1 gene is observed in ~1–2% of patients NSCLC [158,159,160,161], particularly in non-smokers, those with lung adenocarcinomas, and patients without alterations in the EGFR or ALK genes [159,160,162]. Due to the significant ...
Now, the Halder and Thompson groups identify MASK (multiple ankyrin repeats single KH domain; the human homologues are ANKHD1 and ANKRD17) as a novel component of the Hippo pathway that acts as a cofactor for Yorkie and YAP. In an RNAi screen in D. melanogaster, both laboratories ...