The technical variation introduced by sample preparation was more significant than that produced by the HILIC-HRMS method. By using an orthogonal partial least squares (OPLS) model, subtle fold-changes were accurately measured in the urine samples spiked with13C and15N isotope labelled amino acids ...
Assessment of the Acute Toxicity, Uptake and Biotransformation Potential of Benzotriazoles in Zebrafish (Danio rerio) Larvae Combining HILIC- with RPLC-HRMS ... Damalas,Dimitrios,E.,... - 《Environmental Science & Technology Es & T》 被引量: 0发表: 2018年 Assessment of the Acute Toxicity, ...
In the present study, the stability of 27 bioactive peptides with protection at both termini in equine plasma was examined under different incubation conditions, using HILIC coupled to HRMS. Of the 27 peptides, 13 were stable after incubation at 37 degrees C for 72 hr, but the remaining 14...
Orbitrap HRMS化学成分鉴定主成分分析本研究采用亲水作用色谱柱串联四极杆-静电场轨道阱-线性离子阱三合一组合式高分辨质谱仪(HILIC/Orbitrap Fusion Lumos HRMS)建立了快速智能化鉴定瓜蒌皮注射液中化学成分的分析方法.采用Compound Discoverer软件,检索在线数据库ChemSpider和mzCloud,共鉴定了48个化学成分,包括生物碱,氨基酸...
Orbitrap HRMS化学成分鉴定主成分分析本研究采用亲水作用色谱柱串联四极杆-静电场轨道阱-线性离子阱三合一组合式高分辨质谱仪(HILIC/Orbitrap Fusion Lumos HRMS)建立了快速智能化鉴定瓜蒌皮注射液中化学成分的分析方法.采用Compound Discoverer软件,检索在线数据库ChemSpider和mzCloud,共鉴定了48个化学成分,包括生物碱、...
The fast scan speed and high resolution that was introduced by the new generation of high resolution mass spectrometers (HRMS) has enabled to greatly extend the number of protein analyzed per time unit in LC-MS based proteomic studies. UHPLC technology has increased the efficiency of the ...
本研究采用亲水作用色谱柱串联四极杆-静电场轨道阱-线性离子阱三合一组合式高分辨质谱仪(HILIC/Orbitrap Fusion Lumos HRMS)建立了快速智能化鉴定瓜蒌皮注射液中化学成分的分析方法.采用Compound Discoverer软件,检索在线数据库ChemSpider和mzCloud,共鉴定了48个化学成分,包括生物碱、氨基酸、核苷及其碱基等,其中25个通过与...
Two high-resolution mass spectrometry (HRMS) workflows were used to analyze N-glycans, while nuclear magnetic resonance (NMR) was used to generate monosaccharide fingerprints. These state-of-the-art techniques were compared to conventional analysis using hydrophilic interaction chromatography (HILIC) ...
Selective Profiling of Saponins from Gypsophila trichotoma Wend. by HILIC Separation and HRMS Detectiondoi:10.1002/pca.2739Reneta GevrenovaVentzislav BardarovKrum BardarovLaurence Voutquenne-NazabadiokoMax HenryJohn Wiley & Sons, Ltd